Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | NSD2 | O96028 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL475665 | 0.78 | HPGD (0.51) | MEN1KMT2AHTTHPGDALDH1A1 | |
| SCHEMBL14427603 | 0.75 | MEN1 (0.66) | MEN1KMT2AHTTHPGDALDH1A1 | |
| SCHEMBL1006444 | 0.73 | HTT (0.71) | MEN1KMT2AHTTHPGDALDH1A1 | |
| SCHEMBL3348602 | 0.70 | ALDH1A1 (0.45) | MEN1KMT2AHTTHPGDALDH1A1 | |
| SCHEMBL4694648 | 0.70 | HPGD (0.51) | MEN1KMT2AHTTHPGDALDH1A1 | |
| SCHEMBL6430222 | 0.70 | MEN1 (0.63) | MEN1KMT2AHTTHPGDALDH1A1 | |
| SCHEMBL2900339 | 0.69 | KDM4E (0.43) | ALDH1A1TSHRSMN1; SMN2POLBTDP1 | |
| SCHEMBL3351696 | 0.69 | HDAC2 (0.52) | MEN1KMT2AALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL15720840 | 0.69 | RXRA (0.50) | ALDH1A1TSHRKDM4ELMNA | |
| SCHEMBL2964425 | 0.69 | PPARG (0.61) | KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010042030-A1 | ASPARTYL PROTEASE INHIBITORS | MEDIVIR AB (SE) | 2010-04-15 | — | — | WO | disclosed |