SCHEMBL7079413

SCHEMBL7079413

C1=CCc2c([nH]c3ccccc23)C=C1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.41
KMT2A Q03164 4/20 0.41
HSD17B10 Q99714 2/20 0.41
ALDH1A1 P00352 1/20 0.40
GPR3 P46089 1/20 0.40
KDM4E B2RXH2 4/20 0.39
HTR2A P28223 2/20 0.39
HTR2C P28335 2/20 0.39
HTR5A P47898 2/20 0.39
NISCH Q9Y2I1 2/20 0.39
POLB P06746 1/20 0.39
ADRB2 P07550 1/20 0.39
HTR1A P08908 1/20 0.39
MAPT P10636 1/20 0.39
HTR7 P34969 1/20 0.39
HTR6 P50406 1/20 0.39
CA1 P00915 2/20 0.39
CA2 P00918 2/20 0.39
CA4 P22748 2/20 0.39
CA6 P23280 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16311858 0.88 MEN1 (0.36) MEN1KMT2AHSD17B10ALDH1A1GPR3
SCHEMBL5891207 0.87 HSD17B10 (0.44) MEN1KMT2AHSD17B10ALDH1A1GPR3
SCHEMBL20146143 0.84 KIF11 (0.43) MEN1KMT2AHSD17B10ALDH1A1GPR3
SCHEMBL24726998 0.80 HTR7 (0.39) HTR7HTR6
SCHEMBL17413862 0.80 MEN1 (0.33) MEN1KMT2AHSD17B10ALDH1A1GPR3
SCHEMBL23863477 0.77 MAPT (0.46) MEN1KMT2AHSD17B10ALDH1A1KDM4E
SCHEMBL20083348 0.77 KDM4E (0.30) ALDH1A1KDM4EMAPTCYP1A2CYP2C19
SCHEMBL24633146 0.76 GPR3 (0.33) MEN1KMT2AALDH1A1GPR3MAPT
SCHEMBL296017 0.75 HSD17B10 (0.48) MEN1KMT2AHSD17B10ALDH1A1GPR3
SCHEMBL22295873 0.74 MEN1 (0.41) MEN1KMT2AHSD17B10ALDH1A1GPR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4265612-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME, MANUFACTURING METHOD THEREFOR, AND COMPOSITION FOR ORGANIC MATERIAL LAYER LT Materials Co., Ltd. (KR) 2023-10-25 EP disclosed
WO-2023149553-A1 METHOD FOR IMPROVING HARDNESS OF FIRED PRODUCT 日産化学株式会社 2023-08-10 WO disclosed
EP-4074706-A1 DEUTERATED HETEROCYCLIC COMPOUND, ORGANIC LIGHT EMITTING DEVICE INCLUDING THE SAME AND COMPOSITION FOR ORGANIC LAYER OF ORGANIC LIGHT EMITTING DEVICE LG Display Co., Ltd. (KR) 2022-10-19 EP disclosed
EP-3808744-A1 NOVEL COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING SAME LG CHEM, LTD. (KR) 2021-04-21 EP disclosed
EP-0882726-B1 Carbazol-carboxamides as 5-HT1F agonists LILLY CO ELI (US) 2003-05-21 EP disclosed
US-6221884-B1 Carboxamides useful as 5-HT1F agonists ELI LILLY AND COMPANY 2001-04-24 US disclosed
EP-0882726-A1 Carbazol-carboxamides as 5-HT1F agonists ELI LILLY AND COMPANY (US) 1998-12-09 EP disclosed