Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | FABP3 | P05413 | 4/20 | 0.42 |
| ▸ | FABP4 | P15090 | 4/20 | 0.42 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.39 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MAP2 | P11137 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14877176 | 0.85 | ALDH1A1 (0.54) | KMT2ATDP1LMNAMEN1THRB | |
| SCHEMBL11790229 | 0.85 | LMNA (0.57) | KMT2ATDP1LMNAMEN1THRB | |
| SCHEMBL8926741 | 0.83 | MEN1 (0.41) | KMT2ATDP1LMNAMEN1THRB | |
| SCHEMBL6535649 | 0.80 | TDP1 (0.46) | KMT2ATDP1LMNAMEN1THRB | |
| SCHEMBL3416776 | 0.80 | CHAT (0.44) | KMT2AMEN1ALDH1A1FABP3FABP4 | |
| SCHEMBL10533695 | 0.80 | TDP1 (0.46) | KMT2ATDP1LMNAMEN1THRB | |
| SCHEMBL10718423 | 0.78 | TDP1 (0.39) | KMT2ATDP1LMNAMEN1THRB | |
| SCHEMBL308199 | 0.78 | CYP2A6 (0.55) | LMNAALDH1A1FABP3FABP4FABP5 | |
| SCHEMBL14582403 | 0.78 | ALDH1A1 (0.61) | KMT2ATDP1LMNAMEN1THRB | |
| SCHEMBL2781375 | 0.78 | LMNA (0.48) | KMT2ATDP1LMNAMEN1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116621778-A | USP inhibitor, preparation method and application thereof | 北京华森英诺生物科技有限公司 | 2023-08-22 | — | — | CN | disclosed |
| CN-108997122-A | 3- aryl -4- alkoxy benzyl oxide derivative and its preparation method and application | 南方医科大学 | 2018-12-14 | — | — | CN | disclosed |
| CN-108976107-A | 3- aryl -4- alkoxybenzyl amine derivative and its preparation method and application | 南方医科大学 | 2018-12-11 | — | — | CN | disclosed |
| WO-2010067102-A1 | DIAZASPIRO [5.5] UNDECANE DERIVATIVES AND RELATED COMPOUNDS AS MUSCARINIC-RECEPTOR ANTAGONISTS AND BETA-ADRENORECEPTOR AGONISTS FOR THE TREATMENT OF PULMONARY DISORDERS | ASTRAZENECA AB (SE) | 2010-06-17 | — | — | WO | disclosed |