Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 4/20 | 0.41 |
| ▸ | MAOA | P21397 | 4/20 | 0.41 |
| ▸ | MAOB | P27338 | 4/20 | 0.41 |
| ▸ | RCOR1 | Q9UKL0 | 4/20 | 0.41 |
| ▸ | KDM1B | Q8NB78 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8239483 | 0.91 | ALDH1A1 (0.40) | ALDH1A1L3MBTL1CA12CA1CA2 | |
| SCHEMBL1962554 | 0.90 | NOTUM (0.43) | KDM1AMAOAMAOBRCOR1KDM1B | |
| SCHEMBL5853439 | 0.86 | KDM1A (0.54) | KDM1AMAOAMAOBRCOR1KDM1B | |
| SCHEMBL30443816 | 0.86 | KDM1A (0.54) | KDM1AMAOAMAOBRCOR1KDM1B | |
| SCHEMBL1015595 | 0.85 | ALDH1A1 (0.52) | KDM1AMAOAMAOBRCOR1ALDH1A1 | |
| SCHEMBL3344704 | 0.81 | KDM5B (0.52) | HSD17B10MGLLMAPTPKMLMNA | |
| SCHEMBL3348720 | 0.80 | CYP2C19 (0.45) | ALDH1A1L3MBTL1CA12CA1CA2 | |
| SCHEMBL8149394 | 0.76 | SLC2A1 (0.46) | KDM1AMAOAMAOBRCOR1ALDH1A1 | |
| SCHEMBL1965288 | 0.76 | PRKAG1 (0.51) | KDM1AMAOAMAOBRCOR1KDM1B | |
| SCHEMBL13229812 | 0.75 | F10 (0.43) | ALDH1A1ALOX15HSD17B10HPGDMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010042030-A1 | ASPARTYL PROTEASE INHIBITORS | MEDIVIR AB (SE) | 2010-04-15 | — | — | WO | disclosed |
| WO-2010042030-A1 | ASPARTYL PROTEASE INHIBITORS | MEDIVIR AB (SE) | 2010-04-15 | — | — | WO | disclosed |