Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 11/20 | 0.52 |
| ▸ | NPC1 | O15118 | 10/20 | 0.52 |
| ▸ | KLF5 | Q13887 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3348715 | 0.81 | KDM1A (0.41) | PKMMGLLHSD17B10MAPTLMNA | |
| SCHEMBL3348673 | 0.76 | RAB9A (0.65) | KDM5BRAB9ANPC1MGLLHDAC3 | |
| SCHEMBL30443816 | 0.74 | KDM1A (0.54) | RAB9ANPC1PKMMAPTLMNA | |
| SCHEMBL5853439 | 0.74 | KDM1A (0.54) | RAB9ANPC1PKMMAPTLMNA | |
| SCHEMBL8239483 | 0.74 | ALDH1A1 (0.40) | RAB9ANPC1PKMMGLLHSD17B10 | |
| SCHEMBL1962554 | 0.73 | NOTUM (0.43) | PKMMGLLHSD17B10MAPTLMNA | |
| SCHEMBL7272416 | 0.72 | MGLL (0.74) | KDM5BRAB9ANPC1MGLLHDAC2 | |
| SCHEMBL1015595 | 0.71 | ALDH1A1 (0.52) | RAB9ANPC1MGLLHSD17B10SMN1; SMN2 | |
| SCHEMBL4747063 | 0.71 | KDM5B (0.56) | KDM5BRAB9ANPC1MGLLHDAC3 | |
| SCHEMBL4694649 | 0.70 | MCHR1 (0.55) | KDM5BRAB9ANPC1MGLLHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010042030-A1 | ASPARTYL PROTEASE INHIBITORS | MEDIVIR AB (SE) | 2010-04-15 | — | — | WO | disclosed |