Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL335297 | 0.87 | PRMT6 (0.46) | MAPKAPK2ALDH1A1SMN1; SMN2POLBADRB3 | |
| SCHEMBL18575542 | 0.81 | CASR (0.48) | ADRA2CADRA1AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL10243752 | 0.79 | POLB (0.48) | MAPKAPK2ALDH1A1SMN1; SMN2POLBADRB3 | |
| SCHEMBL4370199 | 0.77 | KEAP1 (0.52) | MAPKAPK2ALDH1A1SMN1; SMN2KEAP1POLB | |
| SCHEMBL10100499 | 0.76 | KEAP1 (0.55) | MAPKAPK2ALDH1A1SMN1; SMN2KEAP1POLB | |
| SCHEMBL11420225 | 0.75 | ADRB3 (0.61) | ADRA2CADRA1AADRA1BALDH1A1SMN1; SMN2 | |
| SCHEMBL334407 | 0.74 | OPRK1 (0.50) | MAPKAPK2ADRA2CADRA1AADRA1BALDH1A1 | |
| SCHEMBL335330 | 0.74 | OPRK1 (0.50) | MAPKAPK2ADRA2CADRA1AADRA1BALDH1A1 | |
| SCHEMBL9004208 | 0.74 | CASR (0.42) | ADRA2CADRA1AALDH1A1SMN1; SMN2ADRB3 | |
| Hydrochloric Acid SCHEMBL9216885 | 0.74 | ADRB3 (0.59) | ADRA2CADRA1AADRA1BALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8097708-B2 | 10a-Azalide compound | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2012-01-17 | — | — | US | disclosed |
| US-20090281292-A1 | 10a-Azalide Compound | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2009-11-12 | — | — | US | disclosed |
| EP-1985620-A1 | 10a-AZALIDE COMPOUND | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2008-10-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090281292-A1 | 10a-Azalide Compound | IL17A, AZI2, HDAC9 | MAPKAPK2 3659/4885ADRA2C 3865/4885ADRA1A 3144/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.