Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 13/20 | 0.66 |
| ▸ | HTR1D | P28221 | 3/20 | 0.50 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 2/20 | 0.47 |
| ▸ | HTR2C | P28335 | 2/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | HTR1B | P28222 | 1/20 | 0.41 |
| ▸ | HTR1F | P30939 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3352349 | 0.85 | HTR6 (0.50) | HTR6HTR1DADRB2HTR2AHTR2C | |
| SCHEMBL3353042 | 0.84 | HTR6 (0.47) | HTR6HTR1DADRB2HTR2AHTR2C | |
| SCHEMBL3320875 | 0.84 | HTR1D (0.68) | HTR6HTR1DADRB2HTR2AHTR2C | |
| SCHEMBL2758324 | 0.79 | HTR1D (0.70) | HTR6HTR1DADRB2HTR2AHTR2C | |
| SCHEMBL20307221 | 0.79 | HTR6 (1.00) | HTR6HTR1DADRB2HTR1AHTR1B | |
| SCHEMBL3872427 | 0.79 | MTNR1A (0.55) | HTR6HTR1DHTR1AHTR1BHTR1F | |
| SCHEMBL9400590 | 0.79 | ADRB2 (0.49) | HTR6HTR1DADRB2HTR2A | |
| SCHEMBL3323916 | 0.79 | ADRB2 (0.50) | HTR6HTR1DADRB2HTR2A | |
| SCHEMBL13537251 | 0.78 | HTR6 (0.61) | HTR6HTR1DADRB2HTR2AHTR2C | |
| SCHEMBL12850609 | 0.78 | HTR2A (0.65) | HTR6HTR1DHTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |