Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 5/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.38 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.37 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.36 |
| ▸ | FPR2 | P25090 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TACR2 | P21452 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3354425 | 0.89 | GAA (0.45) | FLT3USP2HSD17B10GAAALDH1A1 | |
| SCHEMBL3352200 | 0.78 | GAA (0.61) | FLT3USP2HSD17B10GAADRD2 | |
| SCHEMBL15943817 | 0.75 | DRD2 (0.46) | FLT3USP2GAADRD2SLC6A4 | |
| SCHEMBL3352205 | 0.75 | PRMT5 (0.44) | FLT3USP2HSD17B10GAADRD2 | |
| SCHEMBL4293328 | 0.75 | FLT3 (0.48) | FLT3USP2HSD17B10GAADRD2 | |
| SCHEMBL3354719 | 0.74 | MCHR1 (0.47) | HSD17B10DRD2ALDH1A1KDM2BTSHR | |
| SCHEMBL15344990 | 0.73 | DRD2 (0.49) | FLT3USP2DRD2SLC6A4ALDH1A1 | |
| SCHEMBL3353454 | 0.72 | DDB1 (0.51) | FLT3HSD17B10GAADRD2SLC6A4 | |
| SCHEMBL14852094 | 0.72 | DRD2 (0.45) | FLT3USP2HSD17B10GAADRD2 | |
| SCHEMBL14852148 | 0.72 | FLT3 (0.45) | FLT3USP2HSD17B10GAADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |