Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | TERT | O14746 | 2/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | CDK9 | P50750 | 2/20 | 0.37 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.37 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 2/20 | 0.36 |
| ▸ | MLLT1 | Q03111 | 1/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.36 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30782239 | 0.77 | KDM2B (0.51) | MCHR1HDAC1DRD2DRD4DRD3 | |
| SCHEMBL21025783 | 0.75 | KDM4E (0.48) | MCHR1HDAC1ALDH1A1 | |
| SCHEMBL3349367 | 0.74 | FLT3 (0.45) | DRD2ALDH1A1TSHRHSD17B10KDM2B | |
| SCHEMBL17678353 | 0.73 | TSHR (0.48) | MCHR1HDAC1TSHRHSD17B10 | |
| SCHEMBL3430045 | 0.73 | SMN1; SMN2 (0.50) | MCHR1HDAC1HPGDMTNR1AMTNR1B | |
| SCHEMBL21026236 | 0.72 | HRH3 (0.48) | — | |
| SCHEMBL3354425 | 0.72 | GAA (0.45) | HDAC1HPGDALDH1A1MAPTHSD17B10 | |
| SCHEMBL3353218 | 0.71 | KCNH2 (0.49) | MCHR1HDAC1HPGDALDH1A1MAPT | |
| SCHEMBL18731878 | 0.71 | HDAC1 (0.47) | MCHR1HDAC1DRD2DRD4DRD3 | |
| SCHEMBL3352914 | 0.71 | HSD17B10 (0.51) | MCHR1HDAC1DRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |