Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23519752 | 0.84 | CYP3A4 (0.50) | ALDH1A1KMT2AHPGDCYP3A4CYP2C9 | |
| SCHEMBL11114523 | 0.77 | ALDH1A1 (0.54) | ALDH1A1KMT2AKDM4EHPGDCYP3A4 | |
| SCHEMBL25086303 | 0.76 | TERT (0.39) | ALDH1A1KMT2AKDM4EPDK2CYP1A2 | |
| SCHEMBL3349457 | 0.74 | GRIA2 (0.57) | CYP1A2 | |
| SCHEMBL8257459 | 0.72 | HPGD (0.51) | ALDH1A1KMT2AKDM4EHPGDCYP3A4 | |
| SCHEMBL3872052 | 0.72 | ESR2 (0.56) | ALDH1A1KMT2AHPGDCYP3A4CYP2C9 | |
| SCHEMBL8262713 | 0.72 | ALDH1A1 (0.49) | ALDH1A1KMT2AKDM4EHPGDCYP3A4 | |
| SCHEMBL11142367 | 0.71 | ALDH1A1 (0.74) | ALDH1A1HPGDCYP3A4CYP2C9CYP1A2 | |
| Hydrochloric Acid SCHEMBL3878146 | 0.71 | ALDH1A1 (0.47) | ALDH1A1KMT2AKDM4EHPGDCYP3A4 | |
| SCHEMBL20929548 | 0.70 | NR1H2 (0.65) | ALDH1A1KMT2AHPGDCYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230069174-A1 | NITROGEN-CONTAINING HETEROCYCLIC AUTOTAXIN INHIBITOR, AND COMPOSITION CONTAINING SAME AND USE THEREOF | SICHUAN HAISCO PHARMACEUTICAL CO., LTD. (CN) | 2023-03-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230069174-A1 | NITROGEN-CONTAINING HETEROCYCLIC AUTOTAXIN INHIBITOR, AND COMPOSITION CONTAINING SAME AND USE THEREOF | ENPP2, NMT2, NMT1 | ALDH1A1 4631/4885KMT2A 2849/4885KDM4E 4075/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.