Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLS | O94925 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 6/20 | 0.47 |
| ▸ | HTR7 | P34969 | 5/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.47 |
| ▸ | DRD2 | P14416 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3349251 | 0.91 | LMNA (0.44) | GLSHTR2AHTR7KCNH2DRD2 | |
| SCHEMBL3355498 | 0.91 | GLS (0.47) | GLSHTR2AHTR7KCNH2DRD2 | |
| SCHEMBL29377201 | 0.87 | GLS (0.50) | GLSHTR2AHTR7KCNH2GPR119 | |
| SCHEMBL3355202 | 0.87 | GLS (0.50) | GLSHTR2AHTR7KCNH2GPR119 | |
| SCHEMBL14910335 | 0.84 | GLS (0.53) | GLSGPR119ALDH1A1SLC6A4 | |
| SCHEMBL31304459 | 0.84 | GLS (0.53) | GLSGPR119ALDH1A1SLC6A4 | |
| SCHEMBL15910780 | 0.82 | GLS (0.51) | GLSLMNAALDH1A1PKMSLC6A4 | |
| SCHEMBL3356648 | 0.82 | GLS (0.44) | GLSHTR2AHTR7KCNH2DRD2 | |
| SCHEMBL3352833 | 0.82 | MAPT (0.45) | GLSHTR2AHTR7KCNH2LMNA | |
| SCHEMBL3357246 | 0.81 | MAPT (0.51) | GLSLMNAGPR119ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |