Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | HTR1B | P28222 | 1/20 | 0.40 |
| ▸ | HTR1F | P30939 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GLS | O94925 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | HTR7 | P34969 | 3/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3349251 | 0.91 | LMNA (0.44) | ALDH1A1NPC1KMT2AHTR1AHTR1B | |
| SCHEMBL3355498 | 0.91 | GLS (0.47) | MAPTALDH1A1CYP1A2KMT2AHPGD | |
| SCHEMBL3356604 | 0.87 | HTR1A (0.52) | MAPTNPC1HTR1AHTR1BHTR1F | |
| SCHEMBL29741245 | 0.86 | GLS (0.44) | MAPTALDH1A1NPC1CYP1A2HTR1A | |
| SCHEMBL3388874 | 0.86 | GLS (0.44) | MAPTALDH1A1NPC1CYP1A2HTR1A | |
| SCHEMBL7807023 | 0.84 | ACHE (0.57) | MAPTALDH1A1KMT2AMEN1ACHE | |
| SCHEMBL30778513 | 0.84 | MAPT (0.46) | MAPTALDH1A1NPC1KMT2AHTR1A | |
| SCHEMBL3357810 | 0.84 | ALDH1A1 (0.40) | MAPTALDH1A1NPC1KMT2AHTR1A | |
| SCHEMBL7804080 | 0.83 | KDM4E (0.52) | MAPTALDH1A1NPC1KMT2ASMN1; SMN2 | |
| SCHEMBL3353374 | 0.82 | ALDH1A1 (0.48) | MAPTALDH1A1NPC1CYP1A2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |