SCHEMBL3350830

SCHEMBL3350830

CCO[Si](OCC)(OCC)c1ccc(C=Cc2ccc([Si](OCC)(OCC)OCC)cc2)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RELA Q04206 2/20 0.42
ESR1 P03372 2/20 0.38
AHR P35869 1/20 0.38
PTGS2 P35354 1/20 0.36
RAB9A P51151 4/20 0.35
CYP3A4 P08684 3/20 0.35
NPC1 O15118 3/20 0.35
CYP1A2 P05177 2/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
KDM4E B2RXH2 1/20 0.35
CYP2D6 P10635 1/20 0.35
CYP2C9 P11712 1/20 0.35
HPGD P15428 1/20 0.35
CYP2C19 P33261 1/20 0.35
TUBB1 Q9H4B7 2/20 0.35
TUBB4A P04350 1/20 0.35
TUBB P07437 1/20 0.35
TUBA3C P0DPH7 1/20 0.35
TUBA1B P68363 1/20 0.35
TUBA4A P68366 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3350829 1.00 RELA (0.42) RELAESR1AHRPTGS2RAB9A
SCHEMBL3417632 0.94 RELA (0.39) RELAESR1AHRPTGS2RAB9A
SCHEMBL3417630 0.94 RELA (0.39) RELAESR1AHRPTGS2RAB9A
SCHEMBL5486605 0.92 RELA (0.55) RELARAB9ACYP3A4CYP1A2SMN1; SMN2
SCHEMBL5486599 0.92 RELA (0.55) RELARAB9ACYP3A4CYP1A2SMN1; SMN2
SCHEMBL27801218 0.90 ALDH1A1 (0.44) RELAESR1AHRPTGS2RAB9A
SCHEMBL3350059 0.86 RELA (0.41) RELARAB9ACYP3A4CYP1A2SMN1; SMN2
SCHEMBL3350053 0.86 RELA (0.41) RELARAB9ACYP3A4CYP1A2SMN1; SMN2
SCHEMBL20478197 0.86 NQO1 (0.35) ESR1
SCHEMBL50701 0.86 NQO1 (0.35) ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10428198-B2 Ultraviolet light absorbing matrix-modified light stabilizing silica particles INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2019-10-01 US claimed
US-20100003204-A1 Nanoparticle hybrid sunscreens ENERGY MATERIALS CORPORATION (US) 2010-01-07 US claimed
CN-113980214-B ABS resin containing DPE derivative, butadiene and styrene star copolymer block and preparation method thereof 大连理工大学 2023-04-28 CN disclosed
CN-113980215-B HIPS resin containing DPE derivative, butadiene, isoprene and styrene star copolymer block and preparation method thereof 大连理工大学 2023-04-28 CN disclosed
CN-113999355-B HIPS resin containing DPE derivative, butadiene and styrene star copolymer blocks and preparation method thereof 大连理工大学 2023-04-28 CN disclosed
CN-113831478-B ABS resin containing DPE derivative, butadiene, isoprene and styrene star copolymer block and preparation method thereof 大连理工大学 2023-04-28 CN disclosed
CN-113912798-B Star block copolymer based on DPE derivatives, butadiene, isoprene and styrene monomers and preparation method thereof 大连理工大学 2023-03-24 CN disclosed
CN-113999355-A HIPS resin containing DPE derivative, butadiene and styrene star copolymer block and preparation method thereof 大连理工大学 2022-02-01 CN disclosed
CN-113980214-A ABS resin containing DPE derivative, butadiene and styrene star copolymer block and preparation method thereof 大连理工大学 2022-01-28 CN disclosed
CN-113980215-A HIPS resin containing DPE derivative, butadiene, isoprene and styrene star copolymer block and preparation method thereof 大连理工大学 2022-01-28 CN disclosed
US-10818493-B2 Silicon-based hardmask ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2020-10-27 US disclosed
US-10428198-B2 Ultraviolet light absorbing matrix-modified light stabilizing silica particles INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2019-10-01 US disclosed
US-20190115209-A1 SILICON-BASED HARDMASK ROHM & HAAS ELECT MAT (US) 2019-04-18 US disclosed
US-10186424-B2 Silicon-based hardmask ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2019-01-22 US disclosed
US-20180366319-A1 SILICON-BASED HARDMASK ROHM & HAAS ELECT MAT (US) 2018-12-20 US disclosed
US-20170210880-A1 ULTRAVIOLET LIGHT ABSORBING MATRIX-MODIFIED LIGHT STABILIZING SILICA PARTICLES INTERNATIONAL BUSINESS MACHINES CORPORATION 2017-07-27 US disclosed
US-20100003204-A1 Nanoparticle hybrid sunscreens ENERGY MATERIALS CORPORATION (US) 2010-01-07 US disclosed