Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 2/20 | 0.35 |
| ▸ | AHR | P35869 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.33 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.33 |
| ▸ | TUBB | P07437 | 1/20 | 0.33 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.33 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.33 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.33 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.33 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.33 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.33 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.33 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.33 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3417630 | 1.00 | RELA (0.39) | RELAESR1AHRNPC1RAB9A | |
| SCHEMBL3350830 | 0.94 | RELA (0.42) | RELAESR1AHRNPC1RAB9A | |
| SCHEMBL3350829 | 0.94 | RELA (0.42) | RELAESR1AHRNPC1RAB9A | |
| SCHEMBL13933201 | 0.88 | ESR1 (0.34) | ESR1KMT2ACYP3A4KDM4ECYP2D6 | |
| SCHEMBL14429555 | 0.88 | ESR1 (0.34) | ESR1KMT2ACYP3A4KDM4ECYP2D6 | |
| SCHEMBL545299 | 0.88 | ESR1 (0.34) | ESR1KMT2ACYP3A4KDM4ECYP2D6 | |
| SCHEMBL5486605 | 0.87 | RELA (0.55) | RELARAB9AKMT2ACYP3A4CYP1A2 | |
| SCHEMBL5486599 | 0.87 | RELA (0.55) | RELARAB9AKMT2ACYP3A4CYP1A2 | |
| SCHEMBL30018341 | 0.85 | ALDH1A1 (0.39) | KMT2AMAPT | |
| SCHEMBL27801218 | 0.85 | ALDH1A1 (0.44) | RELAESR1AHRNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9549996-B2 | Matrix incorporated fluorescent porous and non-porous silica particles for medical imaging | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2017-01-24 | — | — | US | claimed |
| US-9119875-B2 | Matrix incorporated fluorescent porous and non-porous silica particles for medical imaging | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2015-09-01 | — | — | US | claimed |
| US-20150231280-A1 | MATRIX-INCORPORATED FLUORESCENT POROUS AND NON-POROUS SILICA PARTICLES FOR MEDICAL IMAGING | INTERNATIONAL BUSINESS MACHINES CORPORATION | 2015-08-20 | — | — | US | claimed |
| US-20140271894-A1 | MATRIX-INCORPORATED FLUORESCENT POROUS SILICA PARTICLES FOR DRUG DELIVERY | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2014-09-18 | — | — | US | claimed |
| US-20140271481-A1 | MATRIX-INCORPORATED FLUORESCENT POROUS AND NON-POROUS SILICA PARTICLES FOR MEDICAL IMAGING | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2014-09-18 | — | — | US | claimed |
| US-9549996-B2 | Matrix incorporated fluorescent porous and non-porous silica particles for medical imaging | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2017-01-24 | — | — | US | disclosed |
| US-9119875-B2 | Matrix incorporated fluorescent porous and non-porous silica particles for medical imaging | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2015-09-01 | — | — | US | disclosed |
| US-20150231280-A1 | MATRIX-INCORPORATED FLUORESCENT POROUS AND NON-POROUS SILICA PARTICLES FOR MEDICAL IMAGING | INTERNATIONAL BUSINESS MACHINES CORPORATION | 2015-08-20 | — | — | US | disclosed |
| US-20140271894-A1 | MATRIX-INCORPORATED FLUORESCENT POROUS SILICA PARTICLES FOR DRUG DELIVERY | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2014-09-18 | — | — | US | disclosed |
| US-20140271481-A1 | MATRIX-INCORPORATED FLUORESCENT POROUS AND NON-POROUS SILICA PARTICLES FOR MEDICAL IMAGING | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2014-09-18 | — | — | US | disclosed |
| US-8735852-B2 | Matrix-incorporated fluorescent silica for anti-counterfeiting | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2014-05-27 | — | — | US | disclosed |
| US-20130341528-A1 | Matrix-Incorporated Fluorescent Silica with On/Off Functionality for Anti-Counterfeiting | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2013-12-26 | — | — | US | disclosed |
| US-20130270457-A1 | Matrix-Incorporated Fluorescent Silica for Anti-Counterfeiting | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2013-10-17 | — | — | US | disclosed |
| US-7777176-B2 | Composition and method to characterize membranes' defects | ENERGY MATERIALS CORPORATION (US) | 2010-08-17 | — | — | US | disclosed |
| US-20100038526-A1 | Composition and method to characterize membranes' defects | ENERGY MATERIALS CORPORATION | 2010-02-18 | — | — | US | disclosed |
| WO-2010019125-A1 | COMPOSITION AND METHOD TO CHARACTERIZE MEMBRANES' DEFECTS | ENERGY MATERIALS CORPORATION (US) | 2010-02-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130270457-A1 | Matrix-Incorporated Fluorescent Silica for Anti-Counterfeiting | MACF1, SRM, MMP1 | RELA 2658/4885ESR1 4067/4885AHR 4233/4885 |
| US-20130341528-A1 | Matrix-Incorporated Fluorescent Silica with On/Off Functionality for Anti-Counterfeiting | MACF1, MYOF, MIF | RELA 3560/4885ESR1 3202/4885AHR 3346/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.