Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 7/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.41 |
| ▸ | GSK3B | P49841 | 2/20 | 0.39 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.39 |
| ▸ | CASP2 | P42575 | 2/20 | 0.39 |
| ▸ | CASP7 | P55210 | 2/20 | 0.39 |
| ▸ | CASP6 | P55212 | 2/20 | 0.39 |
| ▸ | CASP8 | Q14790 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | GSK3A | P49840 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9006880 | 0.83 | KDM4E (0.46) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL2824441 | 0.81 | KDM4E (0.49) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL166123 | 0.81 | HPGD (0.47) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL28128763 | 0.79 | KDM4E (0.46) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL27494084 | 0.78 | ALDH1A1 (0.45) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL57295 | 0.78 | KDM4E (0.45) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL28192702 | 0.78 | KDM4E (0.45) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL10922058 | 0.77 | KDM4E (0.45) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL28247275 | 0.77 | GSK3B (0.44) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL10922052 | 0.77 | KDM4E (0.45) | KDM4EALDH1A1GAAHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010042851-A1 | ANTIBACTERIAL AMINOGLYCOSIDE ANALOGS | ACHAOGEN, INC. (US) | 2010-04-15 | — | — | WO | disclosed |
| US-5567411-A | ADMINISTERING TO A WARM-BLOODED ANIMAL TO OBTAIN A MAGNETIC RESONANCE IMAGE OF SUBJECT | STATE OF OREGON ACTING BY AND THROUGH THE STATE BOARD OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF OREGON (US) | 1996-10-22 | — | — | US | disclosed |