Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | GSK3B | P49841 | 2/20 | 0.43 |
| ▸ | CASP3 | P42574 | 5/20 | 0.42 |
| ▸ | CASP7 | P55210 | 3/20 | 0.42 |
| ▸ | CASP2 | P42575 | 2/20 | 0.42 |
| ▸ | CASP6 | P55212 | 2/20 | 0.42 |
| ▸ | CASP8 | Q14790 | 2/20 | 0.42 |
| ▸ | PARP1 | P09874 | 5/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | RGS12 | O14924 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL166123 | 0.85 | HPGD (0.47) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL2824441 | 0.82 | KDM4E (0.49) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL2247260 | 0.81 | KDM4E (0.42) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL3908443 | 0.79 | GSK3B (0.48) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL4336651 | 0.79 | KDM4E (0.43) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL10925239 | 0.79 | ALDH1A1 (0.43) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL8356651 | 0.79 | KDM4E (0.43) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL1256987 | 0.79 | KDM4E (0.40) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL2820121 | 0.79 | HPGD (0.45) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL3351153 | 0.78 | KDM4E (0.49) | KDM4EALDH1A1HPGDHSD17B10GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 91 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250313675-A1 | Facile Assembly of Soft Nanoarchitectures and Co-Loading of Hydrophilic and Hydrophobic Molecules via Flash Nanoprecipitation | NORTHWESTERN UNIVERSITY | 2025-10-09 | — | — | US | disclosed |
| US-12162997-B2 | Facile assembly of soft nanoarchitectures and co-loading of hydrophilic and hydrophobic molecules via flash nanoprecipitation | NORTHWESTERN UNIVERSITY (US) | 2024-12-10 | — | — | US | disclosed |
| CN-113365984-B | LOX inhibitors | 癌症研究协会皇家癌症医院 | 2024-10-15 | — | — | CN | disclosed |
| US-20220017516-A1 | LOX INHIBITORS | THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL (GB) | 2022-01-20 | — | — | US | disclosed |
| US-20220002502-A1 | Facile Assembly of Soft Nanoarchitectures and Co-Loading of Hydrophilic and Hydrophobic Molecules via Flash Nanoprecipitation | NATIONAL SCIENCE FOUNDATION | 2022-01-06 | — | — | US | disclosed |
| EP-3880664-A1 | LOX INHIBITORS | The Institute of Cancer Research: Royal Cancer Hospital (GB) | 2021-09-22 | — | — | EP | disclosed |
| US-11124612-B2 | Facile assembly of soft nanoarchitectures and co-loading of hydrophilic and hydrophobic molecules via flash nanoprecipitation | NORTHWESTERN UNIVERSITY (US) | 2021-09-21 | — | — | US | disclosed |
| CN-113365984-A | LOX inhibitors | 癌症研究协会皇家癌症医院 | 2021-09-07 | — | — | CN | disclosed |
| CN-109641891-B | Novel compounds and methods | 维罗纳制药公司 | 2021-05-04 | — | — | CN | disclosed |
| US-20200255603-A1 | Facile Assembly of Soft Nanoarchitectures and Co-Loading of Hydrophilic and Hydrophobic Molecules via Flash Nanoprecipitation | NATIONAL SCIENCE FOUNDATION | 2020-08-13 | — | — | US | disclosed |
| US-5216150-A | Muscle relaxant; enzyme inhibitor and platelet aggutination inhibitor | Hidaka, Hiroyoshi (JP) | 1993-06-01 | — | — | US | disclosed |
| US-5081246-A | Isoquinolino sulfonamino derivatives | Hidaka, Hiroyoshi (JP) | 1992-01-14 | — | — | US | disclosed |
| CN-1044098-A | Compounds with vascular smooth muscle relaxing activity | HIDAKA HIROYOSHI (JP) | 1990-07-25 | — | — | CN | disclosed |
| US-4908365-A | Pharmaceuticals | SOCIETE ANONYME (FR) | 1990-03-13 | — | — | US | disclosed |
| US-4673684-A | Amide derivatives and 5-lipoxygenase inhibitors containing the same as an active ingredient | TERUMO CORPORATION (JP) | 1987-06-16 | — | — | US | disclosed |
| US-4604390-A | FUNGICIDES, ANTITUMOR AGENTS | WARNER-LAMBERT COMPANY (US) | 1986-08-05 | — | — | US | disclosed |
| EP-0157420-A2 | Amide derivatives and 5-lipoxygenase inhibitors containing the same as an active ingredient | TERUMO KABUSHIKI KAISHA trading as TERUMO CORPORATION (JP) | 1985-10-09 | — | — | EP | disclosed |
| US-4542145-A | Substituted N-[(1H-1,2,4-triazol-1-yl)-alkyl]heteroarylcarboxamides | AMERICAN CYANAMID COMPANY (US) | 1985-09-17 | — | — | US | disclosed |
| US-4539416-A | Processes for making thioalkyl carboxamides and amines | THE DOW CHEMICAL COMPANY (US) | 1985-09-03 | — | — | US | disclosed |
| EP-0042440-B1 | FIRE RETARDANT ORGANIC HIGH MOLECULAR COMPOSITION | ACOME, SOCIETE COOPERATIVE DE TRAVAILLEURS (FR) | 1985-03-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220017516-A1 | LOX INHIBITORS | LOXL1, LOX, LOXL2 | KDM4E 849/4885ALDH1A1 122/4885HPGD 152/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.