Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | PRKCA | P17252 | 1/20 | 0.31 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28395655 | 0.88 | FAAH (0.40) | MAPTCA1CA2FAAHLMNA | |
| SCHEMBL335124 | 0.85 | CHRM1 (0.41) | MAPTCA1CA2FAAHCHRM1 | |
| SCHEMBL28889016 | 0.78 | MAPT (0.42) | MAPTCA1CA2FAAHLMNA | |
| SCHEMBL7223715 | 0.76 | CHRM1 (0.44) | MAPTCA1CA2FAAHCHRM1 | |
| SCHEMBL4739524 | 0.76 | FAAH (0.40) | MAPTCA1CA2FAAHCHRM1 | |
| SCHEMBL27563269 | 0.76 | ZDHHC7 (0.46) | CA1CA2LMNACHRM1CHRM3 | |
| SCHEMBL2988148 | 0.76 | FAAH (0.40) | MAPTCA1CA2FAAHCHRM1 | |
| SCHEMBL9269283 | 0.76 | ALOX15 (0.46) | CA1CA2LMNACHRM1CHRM3 | |
| SCHEMBL2990052 | 0.76 | FAAH (0.40) | MAPTCA1CA2FAAHCHRM1 | |
| SCHEMBL7624643 | 0.75 | CHRM1 (0.52) | MAPTCA1CA2CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5252574-A | Hypotensive agents, vision disorder | MERCK & CO., INC. (US) | 1993-10-12 | — | — | US | disclosed |