Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | CNR1 | P21554 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | KRAS | P01116 | 3/20 | 0.45 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TNF | P01375 | 2/20 | 0.43 |
| ▸ | TNFSF11 | O14788 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3354160 | 0.92 | ALDH1A1 (0.50) | ALDH1A1HPGDKDM4EGLAGAA | |
| SCHEMBL3357593 | 0.84 | CNR1 (0.47) | ALDH1A1CNR1KMT2ACNR2 | |
| SCHEMBL3350340 | 0.83 | ALDH1A1 (0.53) | ALDH1A1HPGDKDM4EGLAGAA | |
| SCHEMBL13537370 | 0.81 | ALDH1A1 (0.52) | ALDH1A1HPGDKDM4EGLAGAA | |
| SCHEMBL3357817 | 0.77 | ALDH1A1 (0.53) | ALDH1A1HPGDKDM4EGLAGAA | |
| SCHEMBL948744 | 0.76 | TNFSF11 (0.55) | ALDH1A1KDM4ETNFTNFSF11 | |
| SCHEMBL31735677 | 0.76 | F2RL3 (0.46) | HPGDHSD17B10CNR1L3MBTL1KMT2A | |
| SCHEMBL3357597 | 0.75 | F2RL3 (0.44) | ALDH1A1CNR1KMT2ANPSR1CNR2 | |
| SCHEMBL13537301 | 0.75 | ALDH1A1 (0.52) | ALDH1A1HPGDKDM4EGLAGAA | |
| SCHEMBL3354060 | 0.75 | CNR2 (0.47) | ALDH1A1CNR1KMT2ACNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |