Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | GLA | P06280 | 4/20 | 0.53 |
| ▸ | GAA | P10253 | 4/20 | 0.53 |
| ▸ | HPGD | P15428 | 4/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.53 |
| ▸ | CNR1 | P21554 | 6/20 | 0.51 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 3/20 | 0.42 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3357817 | 0.91 | ALDH1A1 (0.53) | ALDH1A1KDM4EGLAGAAHPGD | |
| SCHEMBL13537370 | 0.85 | ALDH1A1 (0.52) | ALDH1A1KDM4EGLAGAAHPGD | |
| SCHEMBL3351564 | 0.83 | ALDH1A1 (0.50) | ALDH1A1KDM4EGLAGAAHPGD | |
| SCHEMBL13537301 | 0.78 | ALDH1A1 (0.52) | ALDH1A1KDM4EGLAGAAHPGD | |
| SCHEMBL3354160 | 0.77 | ALDH1A1 (0.50) | ALDH1A1KDM4EGLAGAAHPGD | |
| SCHEMBL10517571 | 0.72 | MTOR (0.45) | ALDH1A1GAAHSD17B10POLB | |
| SCHEMBL31735441 | 0.72 | DYRK1A (0.43) | ALDH1A1KDM4EGAAHPGDHSD17B10 | |
| SCHEMBL21650784 | 0.71 | ALDH1A1 (0.61) | ALDH1A1KDM4EGAAHPGDMEN1 | |
| SCHEMBL24166110 | 0.70 | HRH4 (0.47) | ALDH1A1KDM4EGLAGAAHPGD | |
| SCHEMBL30426961 | 0.70 | HRH4 (0.47) | ALDH1A1KDM4EGLAGAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |