SCHEMBL3352420

SCHEMBL3352420

COc1cccc(C(Br)(Br)Br)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.52
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
CA7 P43166 1/20 0.50
CA9 Q16790 1/20 0.50
ALDH1A1 P00352 1/20 0.50
CYP3A4 P08684 1/20 0.50
KIF11 P52732 1/20 0.47
CES2 O00748 1/20 0.45
CES1 P23141 1/20 0.45
ENPP2 Q13822 1/20 0.45
CA4 P22748 1/20 0.44
CHRM5 P08912 1/20 0.44
IDO1 P14902 2/20 0.42
AGXT P21549 2/20 0.42
NPC1 O15118 1/20 0.42
RAB9A P51151 1/20 0.42
PARP1 P09874 1/20 0.42
RELA Q04206 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8408204 0.82 ACHE (0.52) ACHECA1CA2CA7CA9
SCHEMBL146154 0.82 ACHE (0.52) ACHECA1CA2CA7CA9
SCHEMBL26732489 0.80 ACHE (0.50) ACHECA1CA2CA7CA9
SCHEMBL22932513 0.80 ACHE (0.50) ACHECA1CA2CA7CA9
SCHEMBL29782607 0.80 L3MBTL1 (0.58) ACHECA1CA2CA7CA9
SCHEMBL10644920 0.80 ACHE (0.50) ACHECA1CA2CA7CA9
SCHEMBL167016 0.80 L3MBTL1 (0.58) ACHECA1CA2CA7CA9
SCHEMBL4480152 0.80 ACHE (0.50) ACHECA1CA2CA7CA9
Hydrochloric Acid SCHEMBL29893927 0.80 ACHE (0.50) ACHECA1CA2CA7CA9
SCHEMBL23343726 0.78 ACHE (0.48) ACHECA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010046384-A1 A LITHOGRAPHIC PRINTING PLATE AGFA GRAPHICS NV (BE) 2010-04-29 WO disclosed