Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.52 |
| ▸ | AGXT | P21549 | 2/20 | 0.52 |
| ▸ | MAOB | P27338 | 5/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | CCR5 | P51681 | 1/20 | 0.38 |
| ▸ | TACR2 | P21452 | 1/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6232832 | 0.78 | IDO1 (0.48) | IDO1AGXTMAOBAPPMAOA | |
| SCHEMBL8743208 | 0.77 | IDO1 (0.52) | IDO1MAOBAPPMAOAKMT2A | |
| SCHEMBL8817 | 0.77 | IDO1 (0.52) | IDO1AGXTMAOBAPPMAOA | |
| SCHEMBL353572 | 0.77 | IDO1 (0.52) | IDO1AGXTMAOBAPPMAOA | |
| SCHEMBL58206 | 0.76 | TSHR (0.52) | IDO1AGXTMAOBSLC6A2SLC6A3 | |
| SCHEMBL7189732 | 0.76 | IDO1 (0.57) | IDO1AGXTMAOBAPPNPC1 | |
| SCHEMBL10887507 | 0.75 | IDO1 (0.45) | IDO1AGXTMAOBAPPMAOA | |
| SCHEMBL10724826 | 0.74 | APP (0.49) | APPNPC1RAB9AKMT2ANR4A2 | |
| SCHEMBL31273 | 0.73 | IDO1 (0.58) | IDO1AGXTMAOBAPPMAOA | |
| SCHEMBL444754 | 0.73 | LOXL2 (0.41) | HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118215477-A | Mitochondrial pyruvate carrier inhibitors [1,2,4] triazolo [4,3-a ] pyrimidin-7 (8H) -one for the treatment of cancer | MPC治疗中心 | 2024-06-18 | — | — | CN | disclosed |
| WO-2010067102-A1 | DIAZASPIRO [5.5] UNDECANE DERIVATIVES AND RELATED COMPOUNDS AS MUSCARINIC-RECEPTOR ANTAGONISTS AND BETA-ADRENORECEPTOR AGONISTS FOR THE TREATMENT OF PULMONARY DISORDERS | ASTRAZENECA AB (SE) | 2010-06-17 | — | — | WO | disclosed |