SCHEMBL33524980

SCHEMBL33524980

CCCN(C)C(=O)NCCC[Si](OC)(OC)OC

nearest known ligand 0.41

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 2/20 0.41
EPHX1 P07099 4/20 0.36
DNM1 Q05193 2/20 0.34
LMNA P02545 1/20 0.33
MTNR1A P48039 1/20 0.33
MTNR1B P49286 1/20 0.33
ACHE P22303 7/20 0.33
NPC1 O15118 1/20 0.32
ALDH1A1 P00352 1/20 0.32
RAB9A P51151 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13840103 0.86 EPHX2 (0.36) EPHX2EPHX1MTNR1AMTNR1B
SCHEMBL2616732 0.85 EPHX1 (0.37) EPHX1DNM1LMNAACHE
SCHEMBL4417326 0.85 EPHX2 (0.38) EPHX2MTNR1AMTNR1B
SCHEMBL13840101 0.84 EPHX2 (0.40) EPHX2DNM1
SCHEMBL2024703 0.81 CHRNB2 (0.43) EPHX1LMNAMTNR1AMTNR1BNPC1
SCHEMBL22522246 0.81 CHRNB2 (0.33) EPHX2LMNA
SCHEMBL22573784 0.80 ALDH1A1 (0.35) EPHX2LMNAALDH1A1
SCHEMBL19929282 0.79 EPHX1 (0.39) EPHX1LMNAACHEALDH1A1
SCHEMBL3359618 0.78 EPHX1 (0.45) EPHX2EPHX1DNM1LMNAACHE
SCHEMBL2565754 0.78 CA14 (0.33) EPHX1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260092212-A1 SELECTIVE ETCH INHIBITOR COMPOUNDS AND RELATED METHODS ENTEGRIS INC (US) 2026-04-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260092212-A1 SELECTIVE ETCH INHIBITOR COMPOUNDS AND RELATED METHODS APOL1, ATXN2L, SRSF9 EPHX2 1624/4885EPHX1 2736/4885DNM1 3285/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.