SCHEMBL33526514

SCHEMBL33526514

O=C1OCCc2cncc(F)c21

nearest known ligand 0.34

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
RIPK1 Q13546 3/20 0.34
MAOA P21397 1/20 0.33
MAOB P27338 1/20 0.33
BUB1 O43683 1/20 0.32
ALDH1A1 P00352 2/20 0.31
KDM4E B2RXH2 1/20 0.31
HPGD P15428 1/20 0.31
HSD17B10 Q99714 1/20 0.31
DYRK1A Q13627 1/20 0.30
DYRK2 Q92630 1/20 0.30
DYRK1B Q9Y463 1/20 0.30
LMNA P02545 1/20 0.30
TP53 P04637 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL34474845 0.73 BUB1 (0.34) BUB1
SCHEMBL33526452 0.69 MAOA (0.31) MAOAMAOB
SCHEMBL33526277 0.68 MAOA (0.36) MAOAMAOB
SCHEMBL4063497 0.67 KDM4E (0.44) MAOAMAOBALDH1A1KDM4EHPGD
SCHEMBL15466341 0.66 MAOA (0.41) MAOAMAOBALDH1A1DYRK1ADYRK2
SCHEMBL4066514 0.65 GAA (0.43) MAOAMAOBALDH1A1KDM4EHPGD
SCHEMBL4070347 0.65 GAA (0.43) MAOAMAOBALDH1A1KDM4EHPGD
SCHEMBL4065469 0.65 ALDH1A1 (0.43) MAOAMAOBALDH1A1KDM4EHPGD
SCHEMBL4072395 0.64 NPC1 (0.39) MAOAMAOBALDH1A1KDM4EHPGD
SCHEMBL4067369 0.63 MAOA (0.35) MAOAMAOBALDH1A1KDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260091048-A1 GIP RECEPTOR AGONIST COMPOUNDS LILLY CO ELI (US) 2026-04-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260091048-A1 GIP RECEPTOR AGONIST COMPOUNDS GIPR, GLP1R, GPR119 RIPK1 3681/4885MAOA 3712/4885MAOB 3194/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.