SCHEMBL33526694

SCHEMBL33526694

CC(C)(Cn1nc(C(F)(F)F)cc1CN)NC(=O)OC(C)(C)C

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
LMNA P02545 2/20 0.36
CNR2 P34972 1/20 0.34
POLB P06746 2/20 0.33
TSHR P16473 1/20 0.33
AAK1 Q2M2I8 1/20 0.32
PDE4B Q07343 1/20 0.32
PDE11A Q9HCR9 1/20 0.32
PDE10A Q9Y233 1/20 0.32
LATS1 O95835 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2D6 P10635 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32
KDM4E B2RXH2 1/20 0.32
KLKB1 P03952 1/20 0.32
CCR1 P32246 1/20 0.32
CACNA1H O95180 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL33526182 0.85 L3MBTL1 (0.39) TP53L3MBTL1LMNACNR2POLB
SCHEMBL33527256 0.84 LMNA (0.48) TP53L3MBTL1LMNAPOLBTSHR
SCHEMBL31752997 0.84 TP53 (0.36) TP53L3MBTL1LMNACNR2POLB
SCHEMBL33527125 0.84 TRPV1 (0.35) TP53L3MBTL1LMNAPOLBTSHR
SCHEMBL31752066 0.83 TP53 (0.37) TP53L3MBTL1LMNACNR2POLB
SCHEMBL31753407 0.82 GRN (0.41) TP53L3MBTL1LMNACNR2POLB
SCHEMBL31752359 0.81 TP53 (0.36) TP53L3MBTL1LMNACNR2POLB
SCHEMBL31753527 0.81 TP53 (0.38) TP53L3MBTL1LMNACNR2POLB
SCHEMBL31753000 0.81 TP53 (0.38) TP53L3MBTL1LMNACNR2POLB
SCHEMBL34466710 0.80 TP53 (0.35) TP53L3MBTL1LMNACNR2POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260091048-A1 GIP RECEPTOR AGONIST COMPOUNDS LILLY CO ELI (US) 2026-04-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260091048-A1 GIP RECEPTOR AGONIST COMPOUNDS GIPR, GLP1R, GPR119 TP53 4863/4885L3MBTL1 3664/4885LMNA 2816/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.