SCHEMBL33526939

SCHEMBL33526939

CC(C)(C)OC(=O)NC(C)(C)c1ncccn1

nearest known ligand 0.40

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
NAMPT P43490 2/20 0.40
METAP1 P53582 1/20 0.39
RAB9A P51151 2/20 0.38
ATR Q13535 1/20 0.38
MEN1 O00255 1/20 0.38
NPC1 O15118 1/20 0.38
GAA P10253 1/20 0.38
KMT2A Q03164 1/20 0.38
AAK1 Q2M2I8 6/20 0.36
APLNR P35414 1/20 0.36
CYP17A1 P05093 1/20 0.35
EPHX2 P34913 1/20 0.35
GPR119 Q8TDV5 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16793400 0.81 AAK1 (0.45) NAMPTRAB9AMEN1NPC1KMT2A
SCHEMBL1111103 0.80 ADORA2A (0.47) METAP1RAB9AATRMEN1NPC1
SCHEMBL23666719 0.77 HTT (0.37) MEN1KMT2A
SCHEMBL17612599 0.77 CNR2 (0.43) RAB9AATRMEN1NPC1GAA
SCHEMBL29142163 0.77 ATR (0.47) NAMPTMETAP1RAB9AATRAAK1
SCHEMBL27334225 0.74 AAK1 (0.46) ATRAAK1
SCHEMBL30770699 0.74 AAK1 (0.46) ATRAAK1
SCHEMBL1029793 0.74 KDM4E (0.49) NAMPTMETAP1RAB9AATRNPC1
SCHEMBL17654360 0.73 AAK1 (0.50) NAMPTAAK1
SCHEMBL21949678 0.71 AKT1 (0.46) NAMPTMETAP1RAB9AATRMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260091048-A1 GIP RECEPTOR AGONIST COMPOUNDS LILLY CO ELI (US) 2026-04-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260091048-A1 GIP RECEPTOR AGONIST COMPOUNDS GIPR, GLP1R, GPR119 NAMPT 4430/4885METAP1 3908/4885RAB9A 1982/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.