SCHEMBL33527496

SCHEMBL33527496

CC(C)(C)c1ccc2c(c1)Cc1cc(C(F)(F)F)ccc1-2

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP2 O95551 2/20 0.51
KIF11 P52732 1/20 0.49
SLC1A3 P43003 1/20 0.43
SLC1A2 P43004 1/20 0.43
SLC1A1 P43005 1/20 0.43
ESR1 P03372 1/20 0.42
ESR2 Q92731 1/20 0.42
PNMT P11086 4/20 0.40
PARP1 P09874 1/20 0.40
PARP10 Q53GL7 1/20 0.40
NPC1 O15118 1/20 0.39
ALDH1A1 P00352 1/20 0.39
PLA2G1B P04054 1/20 0.39
NFKB1 P19838 1/20 0.39
CASP3 P42574 1/20 0.39
RAB9A P51151 1/20 0.39
NFKB2 Q00653 1/20 0.39
RELA Q04206 1/20 0.39
SENP8 Q96LD8 1/20 0.39
SENP7 Q9BQF6 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29459210 0.90 ALDH1A1 (0.45) TDP2KIF11NPC1ALDH1A1PLA2G1B
SCHEMBL40372 0.90 ALDH1A1 (0.45) TDP2KIF11NPC1ALDH1A1PLA2G1B
SCHEMBL33527314 0.90 TDP2 (0.59) TDP2KIF11SLC1A3SLC1A2SLC1A1
SCHEMBL6552336 0.88 ALDH1A1 (0.44) TDP2KIF11NPC1ALDH1A1PLA2G1B
Lithium SCHEMBL6552341 0.88 ALDH1A1 (0.44) TDP2KIF11NPC1ALDH1A1PLA2G1B
Hydrochloric Acid SCHEMBL28338025 0.86 ALDH1A1 (0.42) TDP2KIF11NPC1ALDH1A1PLA2G1B
SCHEMBL28338024 0.82 ALDH1A1 (0.40) TDP2KIF11NPC1ALDH1A1PLA2G1B
SCHEMBL868504 0.81 ALDH1A1 (0.53) NPC1ALDH1A1PLA2G1BNFKB1CASP3
SCHEMBL33527682 0.81 TSHR (0.46) TDP2PARP10NPC1ALDH1A1PLA2G1B
SCHEMBL27974149 0.79 TDP2 (0.49) TDP2KIF11SLC1A3SLC1A2SLC1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260092028-A1 ONE-POT SYNTHESIS OF SUBSTITUTED FLOURENES CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2026-04-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260092028-A1 ONE-POT SYNTHESIS OF SUBSTITUTED FLOURENES DYRK1B, DYRK2, DYRK4 TDP2 644/4885KIF11 1181/4885SLC1A3 1760/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.