SCHEMBL33527945

SCHEMBL33527945

C[C@H](NC(=O)[C@H](O)c1cc(F)cc(F)c1)C(=O)N[C@H]1N=C(c2ccccc2)c2ccccc2N(C)C1=O

nearest known ligand 0.75

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
PSEN1 P49768 3/20 0.75
PSEN2 P49810 3/20 0.75
APH1B Q8WW43 3/20 0.75
NCSTN Q92542 3/20 0.75
APH1A Q96BI3 3/20 0.75
PSENEN Q9NZ42 3/20 0.75
GSAP A4D1B5 1/20 0.75
SPPL2A Q8TCT8 1/20 0.66
CCKBR P32239 8/20 0.66
NOTCH1 P46531 1/20 0.62
NOTCH3 Q9UM47 1/20 0.62
KCNH2 Q12809 1/20 0.56
SCN9A Q15858 2/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16417117 1.00 PSEN1 (0.75) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL25314617 1.00 PSEN1 (0.75) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL29404290 1.00 PSEN1 (0.75) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL4413298 1.00 PSEN1 (0.75) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL4418478 0.92 PSEN1 (0.65) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL7262602 0.92 PSEN1 (0.65) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL4414764 0.91 PSEN1 (0.75) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL4412727 0.89 PSEN1 (0.62) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL6301705 0.89 PSEN1 (0.71) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL4987740 0.88 PSEN1 (0.77) PSEN1PSEN2APH1BNCSTNAPH1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260094043-A1 METHODS AND SYSTEMS FOR MULTI-TYPE PROBABILISTIC QUANTUM ERROR MITIGATION QEDMA QUANTUM COMPUTING LTD (IL) 2026-04-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260094043-A1 METHODS AND SYSTEMS FOR MULTI-TYPE PROBABILISTIC QUANTUM ERROR MITIGATION GSS, GCLC, PGLS PSEN1 2278/4885PSEN2 1973/4885APH1B 89/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.