SCHEMBL33527951

SCHEMBL33527951

COC(=O)NCc1cccs1

nearest known ligand 0.64

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
POLB P06746 3/20 0.64
HPGD P15428 7/20 0.62
ALDH1A1 P00352 3/20 0.62
USP2 O75604 1/20 0.60
TSHR P16473 2/20 0.58
SMN1; SMN2 Q16637 2/20 0.58
MAPK1 P28482 1/20 0.58
GAA P10253 2/20 0.57
KMT2A Q03164 2/20 0.57
MAPT P10636 2/20 0.57
LMNA P02545 2/20 0.57
KDM4E B2RXH2 1/20 0.57
MEN1 O00255 1/20 0.57
PKM P14618 1/20 0.57
HTT P42858 1/20 0.57
HSD17B10 Q99714 1/20 0.57
RAB9A P51151 2/20 0.55
TRPM8 Q7Z2W7 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9430080 0.85 POLB (0.58) POLBHPGDALDH1A1USP2SMN1; SMN2
SCHEMBL1163822 0.83 CTSK (0.60) POLBHPGDALDH1A1USP2TSHR
SCHEMBL885325 0.81 POLB (0.68) POLBHPGDALDH1A1USP2TSHR
Acetic Acid SCHEMBL4748939 0.81 RAB9A (0.54) POLBHPGDALDH1A1USP2SMN1; SMN2
SCHEMBL14142610 0.81 LMNA (0.80) POLBHPGDALDH1A1USP2TSHR
SCHEMBL18415485 0.81 POLB (0.72) POLBHPGDALDH1A1USP2TSHR
SCHEMBL15890234 0.80 HPGD (0.60) POLBHPGDALDH1A1USP2TSHR
SCHEMBL3561734 0.79 POLB (0.70) POLBHPGDALDH1A1USP2TSHR
SCHEMBL1709325 0.79 HPGD (0.72) POLBHPGDALDH1A1USP2TSHR
SCHEMBL8009042 0.79 HPGD (0.66) POLBHPGDALDH1A1USP2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260090547-A1 BIO-INSECTICIDES FROM WASTE BIOMASS UNIVERSITY OF DELAWARE (US) 2026-04-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260090547-A1 BIO-INSECTICIDES FROM WASTE BIOMASS PTMS, DDT, BCHE POLB 3564/4885HPGD 2297/4885ALDH1A1 205/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.