Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.97 |
| ▸ | JAK2 | O60674 | 1/20 | 0.68 |
| ▸ | PKM | P14618 | 1/20 | 0.64 |
| ▸ | HTT | P42858 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.61 |
| ▸ | PRKCI | P41743 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | THRB | P10828 | 1/20 | 0.58 |
| ▸ | APEX1 | P27695 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.58 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.58 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.58 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2482973 | 0.86 | POLB (0.73) | POLBJAK2PKMHTTALDH1A1 | |
| SCHEMBL2482978 | 0.86 | POLB (0.73) | POLBJAK2PKMHTTALDH1A1 | |
| SCHEMBL13338334 | 0.86 | POLB (0.73) | POLBJAK2PKMHTTALDH1A1 | |
| SCHEMBL1397612 | 0.85 | POLB (0.71) | POLBJAK2PKMHTTALDH1A1 | |
| SCHEMBL11620661 | 0.85 | POLB (0.71) | POLBJAK2PKMHTTALDH1A1 | |
| SCHEMBL385574 | 0.83 | PKM (0.75) | POLBJAK2PKMHTTALDH1A1 | |
| Hydrochloric Acid SCHEMBL11621347 | 0.83 | POLB (0.74) | POLBJAK2PKMHTTALDH1A1 | |
| SCHEMBL334398 | 0.82 | ALDH1A1 (0.70) | POLBPKMHTTALDH1A1HIF1A | |
| SCHEMBL11619511 | 0.81 | POLB (0.66) | POLBJAK2PKMHTTALDH1A1 | |
| SCHEMBL2482865 | 0.81 | JAK2 (1.00) | POLBJAK2PKMHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8097708-B2 | 10a-Azalide compound | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2012-01-17 | — | — | US | disclosed |
| US-20090281292-A1 | 10a-Azalide Compound | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2009-11-12 | — | — | US | disclosed |
| EP-1985620-A1 | 10a-AZALIDE COMPOUND | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2008-10-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090281292-A1 | 10a-Azalide Compound | IL17A, AZI2, HDAC9 | POLB 3348/4885JAK2 1547/4885PKM 4614/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.