Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 4/20 | 0.58 |
| ▸ | SCD5 | Q86SK9 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 2/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.41 |
| ▸ | PDE5A | O76074 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | DRD5 | P21918 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | SCD | O00767 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22498217 | 0.83 | SCD5 (0.51) | RIPK1SCD5KMT2AROCK2ALDH1A1 | |
| SCHEMBL17513396 | 0.83 | SCD5 (0.51) | RIPK1SCD5KMT2AROCK2ALDH1A1 | |
| SCHEMBL1576663 | 0.83 | RIPK1 (0.73) | RIPK1SCD5ESR1ESR2HSP90AA1 | |
| SCHEMBL25319552 | 0.80 | SCD5 (0.47) | RIPK1SCD5KMT2AROCK2ALDH1A1 | |
| SCHEMBL26926756 | 0.80 | USP30 (0.53) | RIPK1SCD5KMT2AROCK2ALDH1A1 | |
| SCHEMBL22505052 | 0.80 | USP30 (0.53) | RIPK1SCD5KMT2AROCK2ALDH1A1 | |
| SCHEMBL3663950 | 0.80 | USP30 (0.53) | RIPK1SCD5KMT2AROCK2ALDH1A1 | |
| SCHEMBL29641537 | 0.80 | USP30 (0.53) | RIPK1SCD5KMT2AROCK2ALDH1A1 | |
| SCHEMBL28171621 | 0.79 | RIPK1 (0.67) | RIPK1SCD5ESR1ESR2HSP90AA1 | |
| SCHEMBL25965056 | 0.77 | BTK (0.48) | RIPK1SCD5KMT2AROCK2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260092061-A1 | COMPOUNDS FOR TARGETED PROTEIN DEGRADATION | AMPHISTA THERAPEUTICS LTD (GB) | 2026-04-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260092061-A1 | COMPOUNDS FOR TARGETED PROTEIN DEGRADATION | BCL9L, RBBP9, BRD9 | RIPK1 1512/4885SCD5 4473/4885KMT2A 4018/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.