SCHEMBL3353411

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL27732330	0.89	RIPK1 (0.56)	RIPK1CDK8CDK7PLK4DCLK1
	SCHEMBL13356975	0.85	RIPK1 (0.55)	RIPK1CDK8CDK7PLK4DCLK1
	SCHEMBL4344288	0.85	CDK8 (0.55)	RIPK1CDK8CDK7PLK4DCLK1
	SCHEMBL2182346	0.85	HPGD (0.51)	RIPK1CDK8CDK7PLK4DCLK1
	SCHEMBL3349836	0.80	CYP1A2 (0.56)	RIPK1CDK8CDK7PLK4DCLK1
	SCHEMBL12410716	0.80	CDK8 (0.67)	RIPK1CDK8CDK7PLK4DCLK1
	SCHEMBL298264	0.78	RIPK1 (0.55)	RIPK1CDK8CDK7PLK4DCLK1
	SCHEMBL415994	0.77	CDK8 (0.68)	RIPK1CDK8CDK7PLK4DCLK1
	SCHEMBL298301	0.77	CDK8 (0.68)	RIPK1CDK8CDK7PLK4DCLK1
	SCHEMBL4117054	0.76	RIPK1 (0.70)	RIPK1CDK8CDK7PLK4DCLK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.