Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK8 | P49336 | 7/20 | 0.55 |
| ▸ | AXL | P30530 | 2/20 | 0.55 |
| ▸ | MAP4K4 | O95819 | 3/20 | 0.55 |
| ▸ | ROS1 | P08922 | 3/20 | 0.55 |
| ▸ | FLT4 | P35916 | 3/20 | 0.55 |
| ▸ | KDR | P35968 | 3/20 | 0.55 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.55 |
| ▸ | MINK1 | Q8N4C8 | 3/20 | 0.55 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.55 |
| ▸ | MAP4K5 | Q9Y4K4 | 3/20 | 0.55 |
| ▸ | CDK7 | P50613 | 2/20 | 0.55 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.55 |
| ▸ | CDK1 | P06493 | 2/20 | 0.55 |
| ▸ | FES | P07332 | 2/20 | 0.55 |
| ▸ | FER | P16591 | 2/20 | 0.55 |
| ▸ | IRAK1 | P51617 | 2/20 | 0.55 |
| ▸ | PKN2 | Q16513 | 2/20 | 0.55 |
| ▸ | MARK2 | Q7KZI7 | 2/20 | 0.55 |
| ▸ | SLK | Q9H2G2 | 2/20 | 0.55 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27732330 | 0.92 | RIPK1 (0.56) | CDK8AXLMAP4K4ROS1FLT4 | |
| SCHEMBL13356975 | 0.85 | RIPK1 (0.55) | CDK8AXLMAP4K4ROS1FLT4 | |
| SCHEMBL3353411 | 0.85 | RIPK1 (0.51) | CDK8AXLMAP4K4ROS1FLT4 | |
| SCHEMBL27677303 | 0.85 | NAMPT (0.57) | CDK8AXLMAP4K4ROS1FLT4 | |
| SCHEMBL298264 | 0.83 | RIPK1 (0.55) | CDK8AXLMAP4K4ROS1FLT4 | |
| SCHEMBL2182346 | 0.81 | HPGD (0.51) | CDK8MAP4K4ROS1FLT4KDR | |
| SCHEMBL12410716 | 0.79 | CDK8 (0.67) | CDK8AXLMAP4K4ROS1FLT4 | |
| SCHEMBL4117054 | 0.79 | RIPK1 (0.70) | CDK8AXLMAP4K4ROS1FLT4 | |
| SCHEMBL29378344 | 0.79 | RIPK1 (0.70) | CDK8AXLMAP4K4ROS1FLT4 | |
| SCHEMBL4128043 | 0.78 | KDR (0.63) | CDK8AXLMAP4K4ROS1FLT4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090274674-A1 | Heterocyclic Oxime Compounds, Process for Their Preparation and Pharmaceutical Compositions Containing Them | LES LABORATOIRES SERVIER (FR) | 2009-11-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090274674-A1 | Heterocyclic Oxime Compounds, Process for Their Preparation and Pharmaceutical Compositions Containing Them | CYP3A4, CYP2C19, CYP3A43 | CDK8 783/4885AXL 424/4885MAP4K4 1638/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.