Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.31 |
| ▸ | ATR | Q13535 | 1/20 | 0.31 |
| ▸ | DHODH | Q02127 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3348230 | 0.88 | ALDH1A1 (0.31) | — | |
| SCHEMBL3347248 | 0.88 | PIM1 (0.32) | DHODH | |
| SCHEMBL3351700 | 0.87 | PIM1 (0.32) | — | |
| SCHEMBL3348871 | 0.86 | PIM1 (0.33) | — | |
| SCHEMBL3347604 | 0.85 | PIM1 (0.30) | — | |
| SCHEMBL3353912 | 0.85 | ALDH1A1 (0.31) | — | |
| SCHEMBL3351413 | 0.78 | DYRK1A (0.40) | — | |
| SCHEMBL25331092 | 0.69 | ALDH1A1 (0.44) | DHODH | |
| Hydrochloric Acid SCHEMBL5121050 | 0.68 | BRD4 (0.34) | — | |
| SCHEMBL3346218 | 0.65 | DYRK1A (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010063487-A1 | PYRAZOLOPYRIMIDINES, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICINE | MERZ PHARMA GMBH & CO. KGAA (DE) | 2010-06-10 | — | — | WO | disclosed |