Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.30 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.30 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.30 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | KIT | P10721 | 1/20 | 0.30 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.30 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3347248 | 0.91 | PIM1 (0.32) | PIM1PIM3PLK3PIM2 | |
| SCHEMBL3348230 | 0.89 | ALDH1A1 (0.31) | PIM1PIM3PLK3PIM2 | |
| SCHEMBL3353912 | 0.88 | ALDH1A1 (0.31) | MEN1KMT2AKITDDR1 | |
| SCHEMBL3348871 | 0.87 | PIM1 (0.33) | PIM1PIM3PLK3PIM2 | |
| SCHEMBL3351700 | 0.86 | PIM1 (0.32) | PIM1PIM3PLK3PIM2 | |
| SCHEMBL3353764 | 0.85 | EGLN1 (0.31) | — | |
| SCHEMBL3346918 | 0.77 | DYRK1A (0.41) | — | |
| SCHEMBL25331092 | 0.69 | ALDH1A1 (0.44) | — | |
| SCHEMBL3347243 | 0.66 | DYRK1A (0.44) | KMT2A | |
| SCHEMBL3351328 | 0.65 | CYP2A6 (0.34) | PIM1PIM3PLK3PIM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010063487-A1 | PYRAZOLOPYRIMIDINES, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICINE | MERZ PHARMA GMBH & CO. KGAA (DE) | 2010-06-10 | — | — | WO | disclosed |