Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 3/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.51 |
| ▸ | ERN1 | O75460 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 2/20 | 0.34 |
| ▸ | AGXT | P21549 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL510448 | 0.88 | GRM5 (0.44) | GRM5FFAR1IDO1AGXTCYP2D6 | |
| SCHEMBL15688010 | 0.84 | TSHR (0.47) | GRM5FFAR1CYP2D6HRH3MAOB | |
| SCHEMBL22894412 | 0.81 | FFAR1 (0.55) | GRM5FFAR1ERN1IDO1AGXT | |
| SCHEMBL2797815 | 0.81 | GRM5 (0.38) | GRM5IDO1CYP2D6HRH3 | |
| SCHEMBL3346401 | 0.80 | ALDH1A1 (0.50) | GRM5FFAR1MAOB | |
| SCHEMBL24969103 | 0.79 | GRM5 (0.38) | GRM5CYP2D6HRH3 | |
| SCHEMBL3351697 | 0.79 | FFAR1 (0.48) | GRM5FFAR1CYP2D6HRH3 | |
| SCHEMBL18316997 | 0.79 | FFAR1 (0.42) | GRM5FFAR1MAOB | |
| SCHEMBL19440746 | 0.78 | CYP2D6 (0.39) | GRM5FFAR1CYP2D6HRH3 | |
| SCHEMBL8850812 | 0.78 | HRH3 (0.47) | GRM5CYP2D6HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010063487-A1 | PYRAZOLOPYRIMIDINES, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICINE | MERZ PHARMA GMBH & CO. KGAA (DE) | 2010-06-10 | — | — | WO | disclosed |