Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.43 |
| ▸ | IDH1 | O75874 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | PRKDC | P78527 | 1/20 | 0.38 |
| ▸ | MIF | P14174 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.37 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.37 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.37 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 4/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18316997 | 0.87 | FFAR1 (0.42) | ALDH1A1FFAR1GRM5GABRA1GABRG2 | |
| SCHEMBL43368 | 0.82 | ALDH1A1 (0.51) | ALDH1A1CYP3A4FFAR1IDH1GABRA1 | |
| SCHEMBL3353828 | 0.80 | GRM5 (0.51) | FFAR1GRM5MAOB | |
| SCHEMBL4713709 | 0.80 | GRM5 (0.66) | ALDH1A1CYP3A4GRM5 | |
| SCHEMBL4773202 | 0.79 | ALDH1A1 (0.56) | ALDH1A1CYP3A4FFAR1IDH1PRKDC | |
| SCHEMBL2659356 | 0.79 | ALDH1A1 (0.56) | ALDH1A1CYP3A4FFAR1IDH1MAOB | |
| SCHEMBL3446231 | 0.79 | FFAR1 (0.49) | ALDH1A1FFAR1GABRA1GABRG2GABRB3 | |
| SCHEMBL15688010 | 0.78 | TSHR (0.47) | FFAR1GRM5MAOB | |
| SCHEMBL6709375 | 0.78 | ALDH1A1 (0.73) | ALDH1A1CYP3A4IDH1PRKDCMIF | |
| SCHEMBL29096823 | 0.77 | LMNA (0.46) | FFAR1GABRA1GABRG2GABRB3GABRA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010063487-A1 | PYRAZOLOPYRIMIDINES, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICINE | MERZ PHARMA GMBH & CO. KGAA (DE) | 2010-06-10 | — | — | WO | disclosed |