Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3358211 | 0.92 | MAPT (0.47) | ALDH1A1HPGDKMT2ALMNAPOLB | |
| SCHEMBL3351542 | 0.91 | ALDH1A1 (0.46) | ALDH1A1HPGDKMT2ALMNAPOLB | |
| SCHEMBL3358890 | 0.89 | POLB (0.52) | ALDH1A1L3MBTL1LMNAPOLBGAA | |
| SCHEMBL2075770 | 0.82 | POLB (0.47) | ALDH1A1HPGDKMT2ALMNAPOLB | |
| SCHEMBL7508094 | 0.80 | CDK2 (0.46) | L3MBTL1KMT2ALMNAPOLBMEN1 | |
| SCHEMBL13537346 | 0.79 | KMT2A (0.44) | ALDH1A1KMT2AGAACYP1A2CYP2D6 | |
| SCHEMBL5327849 | 0.79 | CDK2 (0.56) | ALDH1A1L3MBTL1KMT2APOLBMEN1 | |
| SCHEMBL6488744 | 0.79 | MAPT (0.49) | LMNAPOLBCDK2NPC1MAPT | |
| SCHEMBL3352674 | 0.78 | CDK2 (0.44) | ALDH1A1L3MBTL1KMT2APOLBMEN1 | |
| SCHEMBL1559389 | 0.77 | KMT2A (0.65) | ALDH1A1KMT2ALMNAPOLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |