Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | AR | P10275 | 2/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3358211 | 0.99 | MAPT (0.47) | ALDH1A1HPGDMEN1KMT2AMAPT | |
| SCHEMBL3353911 | 0.91 | ALDH1A1 (0.45) | ALDH1A1HPGDMEN1KMT2AMAPT | |
| SCHEMBL2075770 | 0.89 | POLB (0.47) | ALDH1A1HPGDMEN1KMT2AMAPT | |
| SCHEMBL3358890 | 0.89 | POLB (0.52) | ALDH1A1MAPTPOLBSMN1; SMN2GAA | |
| SCHEMBL7508094 | 0.80 | CDK2 (0.46) | MEN1KMT2AMAPTPOLBNPC1 | |
| SCHEMBL13537323 | 0.79 | ALOX5 (0.42) | ALDH1A1HPGDMEN1KMT2APOLB | |
| SCHEMBL6488744 | 0.79 | MAPT (0.49) | MAPTPOLBNPC1LMNACDK2 | |
| SCHEMBL5327849 | 0.79 | CDK2 (0.56) | ALDH1A1MEN1KMT2AMAPTPOLB | |
| SCHEMBL3352674 | 0.78 | CDK2 (0.44) | ALDH1A1MEN1KMT2AMAPTPOLB | |
| SCHEMBL2844171 | 0.77 | MAPT (0.59) | ALDH1A1HPGDMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |