Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 1/20 | 0.50 |
| ▸ | JMJD6 | Q6NYC1 | 4/20 | 0.49 |
| ▸ | CA12 | O43570 | 3/20 | 0.44 |
| ▸ | CA1 | P00915 | 3/20 | 0.44 |
| ▸ | CA2 | P00918 | 3/20 | 0.44 |
| ▸ | CA7 | P43166 | 3/20 | 0.44 |
| ▸ | CA9 | Q16790 | 3/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.44 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.44 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.44 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.44 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.44 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.44 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.44 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.44 |
| ▸ | KDM5A | P29375 | 1/20 | 0.41 |
| ▸ | KDM5C | P41229 | 1/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29851835 | 0.84 | KDM4E (0.51) | JMJD6CA12CA1CA2CA7 | |
| SCHEMBL1758901 | 0.84 | KDM4E (0.51) | JMJD6CA12CA1CA2CA7 | |
| SCHEMBL508971 | 0.81 | JMJD6 (0.52) | PIK3CAJMJD6CA12CA1CA2 | |
| SCHEMBL28940585 | 0.79 | MEN1 (0.36) | GABRA1GABRA5GABRG2GABRB3GABRA3 | |
| SCHEMBL2928318 | 0.79 | CYP3A4 (0.50) | CA12CA1CA2CA7CA9 | |
| SCHEMBL5680334 | 0.76 | L3MBTL1 (0.46) | PIK3CAJMJD6HSD17B2MEN1KMT2A | |
| SCHEMBL3347534 | 0.76 | JMJD6 (0.46) | PIK3CAJMJD6MEN1NPC1RAB9A | |
| SCHEMBL936599 | 0.76 | ACACB (0.53) | CA12CA1CA2CA7CA9 | |
| SCHEMBL363249 | 0.76 | JMJD6 (0.58) | PIK3CAJMJD6CA12CA1CA2 | |
| SCHEMBL30171421 | 0.76 | JMJD6 (0.76) | PIK3CAJMJD6CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010063487-A1 | PYRAZOLOPYRIMIDINES, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICINE | MERZ PHARMA GMBH & CO. KGAA (DE) | 2010-06-10 | — | — | WO | disclosed |