Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.46 |
| ▸ | JMJD6 | Q6NYC1 | 3/20 | 0.43 |
| ▸ | BRAF | P15056 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5679770 | 0.84 | KDM4C (0.44) | L3MBTL1KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL4122249 | 0.78 | JMJD6 (0.55) | L3MBTL1HSD17B2JMJD6BRAFKMT2A | |
| SCHEMBL3354058 | 0.76 | PIK3CA (0.50) | HSD17B2JMJD6KMT2AMEN1CYP1A2 | |
| SCHEMBL508971 | 0.74 | JMJD6 (0.52) | HSD17B2JMJD6KDM4EALDH1A1CYP1A2 | |
| Ethyltrimethoxy Benzoate SCHEMBL4410910 | 0.73 | KMT2A (0.66) | L3MBTL1HSD17B2KMT2AMEN1KDM4E | |
| SCHEMBL5680000 | 0.73 | GAA (0.39) | — | |
| SCHEMBL7456502 | 0.71 | JMJD6 (0.55) | HSD17B2JMJD6CYP1A2PIK3CACYP3A4 | |
| SCHEMBL2765372 | 0.70 | HPGD (0.61) | KMT2AMEN1KDM4EALDH1A1CYP1A2 | |
| SCHEMBL3347534 | 0.70 | JMJD6 (0.46) | JMJD6KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL3710171 | 0.70 | KDM4E (0.52) | L3MBTL1JMJD6KDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1403249-B1 | CYCLIC DIAMINE COMPOUNDS BEARING SIX-MEMBERED CYCLIC GROUPS | KOWA CO (JP) | 2006-03-15 | — | — | EP | disclosed |
| EP-1403249-A1 | CYCLIC DIAMINE COMPOUNDS BEARING SIX-MEMBERED CYCLIC GROUPS | Kowa Co., Ltd. (JP) | 2004-03-31 | — | — | EP | disclosed |
| US-6509329-B1 | Inhibitory effects on both cell adhesion and cell infiltration and is useful as a medicine for prevention or treatment of diseases such as allergy, asthma, rheumatism, arteriosclerosis and inflammation | KOWA CO., LTD. (JP) | 2003-01-21 | — | — | US | disclosed |