Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATF4 | P18848 | 4/20 | 0.34 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3359150 | 0.89 | ADAMTS5 (0.40) | ATF4ADAMTS5ALDH1A1 | |
| SCHEMBL3358886 | 0.88 | ADAMTS5 (0.40) | ATF4ADAMTS5ALDH1A1MEN1KMT2A | |
| SCHEMBL3355773 | 0.85 | MCHR1 (0.37) | ATF4ADAMTS5MCHR1DRD2 | |
| SCHEMBL3355261 | 0.84 | ADAMTS5 (0.42) | ATF4ADAMTS5ALDH1A1MEN1KMT2A | |
| SCHEMBL3353515 | 0.80 | ALDH1A1 (0.38) | ATF4ALDH1A1 | |
| SCHEMBL13330973 | 0.79 | ALDH1A1 (0.36) | ATF4ALDH1A1MEN1KMT2A | |
| SCHEMBL3355744 | 0.79 | ALDH1A1 (0.36) | ATF4ALDH1A1 | |
| SCHEMBL3353581 | 0.78 | ALDH1A1 (0.36) | ATF4ALDH1A1 | |
| SCHEMBL3353173 | 0.78 | ALDH1A1 (0.36) | ATF4ALDH1A1 | |
| SCHEMBL3354403 | 0.77 | ALDH1A1 (0.36) | ATF4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100152160-A1 | NOVEL BENZODIOXANE AND BENZOXAZINE DERIVATIVES USEFUL AS CC CHEMOKINE RECEPTOR LIGANDS | KHAMRAI UTTAM | 2010-06-17 | — | — | US | disclosed |
| WO-2010068881-A1 | NOVEL BENZODIOXANE AND BENZOXAZINE DERIVATIVES USEFUL AS CC CHEMOKINE RECEPTOR LIGANDS | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-06-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100152160-A1 | NOVEL BENZODIOXANE AND BENZOXAZINE DERIVATIVES USEFUL AS CC CHEMOKINE RECEPTOR LIGANDS | CCR1, CCR4, CCR5 | ATF4 2359/4885ADAMTS5 2540/4885MCHR1 201/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.