Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 7/20 | 0.61 |
| ▸ | F2 | P00734 | 1/20 | 0.48 |
| ▸ | F10 | P00742 | 1/20 | 0.48 |
| ▸ | F7 | P08709 | 1/20 | 0.48 |
| ▸ | F3 | P13726 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 2/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1484086 | 0.88 | F2 (0.50) | ELANEF2F10F7F3 | |
| SCHEMBL5110242 | 0.81 | ELANE (0.62) | ELANEF2F10F7F3 | |
| SCHEMBL6082809 | 0.76 | ELANE (1.00) | ELANEMEN1KMT2APDE10AC1R | |
| SCHEMBL5555368 | 0.76 | ELANE (0.50) | ELANEMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL3354495 | 0.76 | ELANE (0.56) | ELANEF2F10F7F3 | |
| SCHEMBL4468712 | 0.74 | HCAR2 (0.50) | ELANEF2F10F7F3 | |
| SCHEMBL2076414 | 0.73 | ELANE (0.47) | ELANEF2F10F7F3 | |
| SCHEMBL26438943 | 0.72 | F2 (0.50) | ELANEF2F10F7F3 | |
| SCHEMBL2301620 | 0.72 | ELANE (0.59) | ELANEF2F10F7F3 | |
| SCHEMBL7391149 | 0.71 | TP53 (0.63) | F2F10F7F3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050203110-A1 | Mitotic kinesin inhibitors | COLEMAN PAUL J (US) | 2005-09-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050203110-A1 | Mitotic kinesin inhibitors | KIF2C, KIF5B, KIF18B | ELANE 4218/4885F2 4876/4885F10 4528/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.