Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.48 |
| ▸ | HTR7 | P34969 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.38 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | CCR2 | P41597 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3357957 | 0.81 | HTR7 (0.63) | ACHEHTR7SIGMAR1HRH4SIRT6 | |
| SCHEMBL3352228 | 0.79 | HTR7 (0.44) | ACHEHTR7HRH4SIRT6HIF1A | |
| SCHEMBL3351951 | 0.79 | NOTUM (0.40) | NOTUMHRH4ALDH1A1CNR2 | |
| SCHEMBL13537342 | 0.78 | NOTUM (0.40) | NOTUMCYP1A2ALDH1A1CYP2D6CNR2 | |
| SCHEMBL1629608 | 0.76 | CYP1A2 (0.59) | ACHEHTR7CYP1A2LMNAALDH1A1 | |
| SCHEMBL3354696 | 0.75 | HTR7 (0.58) | ACHEHTR7SIGMAR1CYP1A2HRH4 | |
| SCHEMBL30860194 | 0.72 | ACHE (0.55) | ACHEHTR7HRH4SIRT6LMNA | |
| SCHEMBL20853224 | 0.72 | NOTUM (0.49) | NOTUM | |
| SCHEMBL10413622 | 0.72 | MAPT (0.51) | ACHEHTR7CYP1A2LMNAALDH1A1 | |
| SCHEMBL31735794 | 0.71 | ACHE (0.57) | ACHEHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |