SCHEMBL3355210

SCHEMBL3355210

O=c1c(-c2ccc(OS(=O)(=O)O)cc2)coc2cc(OS(=O)(=O)O)ccc12

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
STS P08842 1/20 0.65
XDH P47989 1/20 0.61
ALDH2 P05091 13/20 0.58
MAOA P21397 8/20 0.58
MAOB P27338 8/20 0.58
MAPT P10636 6/20 0.57
ALDH1A1 P00352 5/20 0.57
SMN1; SMN2 Q16637 5/20 0.57
KDM4E B2RXH2 4/20 0.57
TP53 P04637 3/20 0.57
CYP3A4 P08684 3/20 0.57
HPGD P15428 3/20 0.57
MEN1 O00255 3/20 0.57
KMT2A Q03164 3/20 0.57
HDAC6 Q9UBN7 3/20 0.57
CYP2D6 P10635 2/20 0.57
CYP2C9 P11712 2/20 0.57
CYP2C19 P33261 2/20 0.57
HSD17B10 Q99714 2/20 0.57
BCL2 P10415 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17938824 0.94 XDH (0.71) STSXDHALDH2MAOAMAOB
SCHEMBL571388 0.91 MAOA (0.71) XDHALDH2MAOAMAOBMAPT
SCHEMBL18872545 0.84 STS (0.66) STSXDHALDH2MAOAMAOB
SCHEMBL17991978 0.82 MAPT (0.50) STSXDHALDH2MAOAMAOB
SCHEMBL17988679 0.82 STS (0.48) STSXDHALDH2MAOAMAOB
SCHEMBL16401100 0.82 XDH (0.73) XDHALDH2MAOAMAOBMAPT
SCHEMBL17938829 0.81 NPC1 (0.67) XDHALDH2MAOAMAOBMAPT
SCHEMBL12238001 0.81 STS (0.61) STSXDHALDH2MAOAMAOB
SCHEMBL12325763 0.81 STS (0.76) STSXDHALDH2MAOAMAOB
SCHEMBL17991990 0.80 MAPT (0.58) STSXDHMAOAMAOBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023150072-A1 COMPOSITIONS AND METHODS FOR THE PRESERVATION OF PLANT MATTER SINCLAIR DAVID A (US) 2023-08-10 WO claimed
US-20230255989-A1 GLYCAN COMPOSITIONS AND USES THEREOF DSM NUTRITIONAL PRODUCTS LLC (US) 2023-08-17 US disclosed
WO-2023150072-A1 COMPOSITIONS AND METHODS FOR THE PRESERVATION OF PLANT MATTER SINCLAIR DAVID A (US) 2023-08-10 WO disclosed
US-11229660-B2 Glycan therapeutics and method of treating conditions associated with TMAO KALEIDO BIOSCIENCES, INC. (US) 2022-01-25 US disclosed
EP-3862002-A1 GLYCAN THERAPEUTICS AND RELATED METHODS THEREOF Kaleido Biosciences, Inc. (US) 2021-08-11 EP disclosed
US-20210137956-A1 GLYCAN COMPOSITIONS AND USES THEREOF HERCULES CAPITAL, INC. 2021-05-13 US disclosed
US-20210113596-A1 GLYCAN THERAPEUTICS AND RELATED METHODS THEREOF KALEIDO BIOSCIENCES, INC. (US) 2021-04-22 US disclosed
US-10881676-B2 Glycan therapeutics and related methods thereof KALEIDO BIOSCIENCES, INC. (US) 2021-01-05 US disclosed
EP-3354282-B1 GLYCAN THERAPEUTICS AND RELATED METHODS THEREOF KALEIDO BIOSCIENCES INC (US) 2020-12-30 EP disclosed
US-10702542-B2 Glycan therapeutics and related methods thereof KALEIDO BIOSCIENCES, INC. (US) 2020-07-07 US disclosed
EP-3071235-A1 GLYCAN THERAPEUTICS AND RELATED METHODS THEREOF Kaleido Biosciences, Inc. (US) 2016-09-28 EP disclosed
WO-2016122889-A1 GLYCAN THERAPEUTICS AND RELATED METHODS THEREOF KALEIDO BIOSCIENCES, INC. (US) 2016-08-04 WO disclosed
US-20160213702-A1 GLYCAN THERAPEUTICS AND RELATED METHODS THEREOF KALEIDO BIOSCIENCES, INC. (US) 2016-07-28 US disclosed
EP-2898923-A2 Isoflavones for regulating sirtuin gene expression Nestec S.A. (CH) 2015-07-29 EP disclosed
US-20140234271-A1 COMPOSITIONS FOR PROLIFERATION OF CELLS AND RELATED METHODS THE HOSPITAL FOR SICK CHILDREN (CA) 2014-08-21 US disclosed
US-8748177-B2 Compositions for proliferation of cells and related methods THE HOSPITAL FOR SICK CHILDREN (CA) 2014-06-10 US disclosed
US-20140039047-A1 METHODS FOR REGULATING SIRTUIN GENE EXPRESSION PAN YUANLONG (US) 2014-02-06 US disclosed
US-20140037583-A1 METHODS AND COMPOSITIONS SUITABLE FOR PREVENTING AND TREATING HYPERLEPTINEMIA PAN YUANLONG (US) 2014-02-06 US disclosed
US-20110301105-A1 COMPOSITIONS FOR PROLIFERATION OF CELLS AND RELATED METHODS THE HOSPITAL FOR SICK CHILDREN (CA) 2011-12-08 US disclosed
WO-2010039679-A1 COMPOSITIONS FOR PROLIFERATION OF CELLS AND RELATED METHODS THE HOSPITAL FOR SICK CHILDREN (CA) 2010-04-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140234271-A1 COMPOSITIONS FOR PROLIFERATION OF CELLS AND RELATED METHODS MKI67, KRT18, PROX1 STS 1309/4885XDH 4441/4885ALDH2 1826/4885
US-20110301105-A1 COMPOSITIONS FOR PROLIFERATION OF CELLS AND RELATED METHODS MKI67, KRT18, PROX1 STS 1309/4885XDH 4441/4885ALDH2 1826/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.