Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 5/20 | 0.57 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.53 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | CXCL8 | P10145 | 2/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.53 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | THPO | P40225 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4144845 | 1.00 | PTGS2 (0.57) | PTGS2PTGS1MAPTCXCR1CXCR2 | |
| SCHEMBL4486188 | 0.91 | AKR1C3 (0.50) | PTGS2PTGS1MAPTCXCR1CXCR2 | |
| SCHEMBL8522917 | 0.90 | PTGS1 (0.55) | PTGS2PTGS1MAPTCXCR1CXCR2 | |
| SCHEMBL13668901 | 0.88 | PTGS1 (0.53) | PTGS2PTGS1MAPTCXCR1CXCR2 | |
| SCHEMBL2998970 | 0.88 | PTGS1 (0.47) | PTGS2PTGS1MAPTCXCR1CXCR2 | |
| SCHEMBL1122739 | 0.86 | BCL2 (0.64) | PTGS2PTGS1MAPTALDH1A1LMNA | |
| SCHEMBL8576518 | 0.86 | PTGS1 (0.55) | PTGS2PTGS1MAPTCXCR1CXCR2 | |
| SCHEMBL8523457 | 0.86 | PTGS1 (0.55) | PTGS2PTGS1MAPTCXCR1CXCR2 | |
| SCHEMBL7038218 | 0.86 | MAPT (0.50) | PTGS2PTGS1MAPTCXCR1CXCR2 | |
| SCHEMBL8462914 | 0.85 | PTGS1 (0.50) | PTGS2PTGS1MAPTCXCR1CXCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1599175-A2 | IMIDAZOPYRIDINES CONTAINING COMBINATIONS AND THEIR USE IN TREATING GASTROINTESTINAL INFLAMMATORY DISORDERS | ALTANA Pharma AG (DE) | 2005-11-30 | — | — | EP | claimed |
| WO-2005074930-A1 | PHARMACEUTICAL COMBINATIONS OF (S) -PANTOPRAZOLE WITH NSAID OR CORTICOSTEROIDS | ALTANA PHARMA AG (DE) | 2005-08-18 | — | — | WO | claimed |
| WO-2004071391-A2 | IMIDAZOPYRIDINES CONTAINING COMBINATIONS AND THEIR USE IN TREATING GASTROINTESTINAL INFLAMMATORY DISORDERS | ALTANA PHARMA AG (DE) | 2004-08-26 | — | — | WO | claimed |
| JP-4069356-A | — | — | None | — | — | JP | disclosed |
| JP-4069356-A | — | — | None | — | — | JP | disclosed |
| WO-2019046201-A1 | METHODS AND COMPOSITIONS TO INHIBIT ADVERSE EFFECTS ASSOCIATED WITH VACCINATIONS | SEN-JAM Pharmaceutical LLC (US) | 2019-03-07 | — | — | WO | disclosed |
| CN-102743341-B | Dexketoprofen tromethamine sustained release particles and preparation method and sustained release medicinal preparation thereof | XI AN DETEN PHARMACEUTICAL CO LTD | 2014-02-26 | — | — | CN | disclosed |
| CN-101679829-B | Photocurable Adhesive Composition | SEKISUI CHEMICAL CO LTD | 2013-10-30 | — | — | CN | disclosed |
| WO-2013022410-A2 | PRODUCTION METHOD FOR EFFERVESCENT FORMULATIONS COMPRISING DEXKETOPROFEN | BILGIC MAHMUT (TR) | 2013-02-14 | — | — | WO | disclosed |
| CN-102743341-A | Dexketoprofen tromethamine sustained release particles and preparation method and sustained release medicinal preparation thereof | XI AN DETEN PHARMACEUTICAL CO LTD | 2012-10-24 | — | — | CN | disclosed |
| JP-2010215862-A | POSTCURE TAPE | SEKISUI CHEM CO LTD | 2010-09-30 | — | — | JP | disclosed |
| US-4937375-A | (Phenylethenyl)phenylpropionic acid and its ester, and method for producing (benzoylphenyl)propionic acid or its ester | NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) | 1990-06-26 | — | — | US | disclosed |
| US-4922052-A | (Vinylphenyl)phenylmethane and method for producing (benzoylphenyl) propionic acid | NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) | 1990-05-01 | — | — | US | disclosed |
| US-4922052-A | (Vinylphenyl)phenylmethane and method for producing (benzoylphenyl) propionic acid | NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) | 1990-05-01 | — | — | US | disclosed |
| EP-0283038-A1 | (Vinylphenyl)phenylmethane and method for producing (benzoylphenyl)propionic acid | NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) | 1988-09-21 | — | — | EP | disclosed |
| EP-0282065-A2 | (Phenylethenyl) phenylpropionic acid and its ester, and method for producing (benzoylphenyl) propionic acid or its ester | NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) | 1988-09-14 | — | — | EP | disclosed |
| EP-0282066-A2 | (Phenylethenyl) phenylpropionaldehyde and method for producing (benzoylphenyl) propionic acid using the same | NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) | 1988-09-14 | — | — | EP | disclosed |
| US-4465855-A | ANTIREUMATIC & ANTIINFLAMMATORIES | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT (HU) | 1984-08-14 | — | — | US | disclosed |
| US-4385004-A | Esters of ortho-allylphenol useful for the preparation of arylacetic acid derivatives | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT. (HU) | 1983-05-24 | — | — | US | disclosed |
| US-4317920-A | ANTIRHEUMATIC AGENTS, ANTIINFLAMMATORY AGENTS | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT. (HU) | 1982-03-02 | — | — | US | disclosed |