Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 4/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.55 |
| ▸ | LIG1 | P18858 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | BCL2 | P10415 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.44 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4144845 | 0.90 | PTGS2 (0.57) | PTGS1PTGS2MAPTKMT2ALMNA | |
| SCHEMBL3355855 | 0.90 | PTGS2 (0.57) | PTGS1PTGS2MAPTKMT2ALMNA | |
| SCHEMBL28518456 | 0.86 | LIG1 (0.61) | LIG1MAPTKMT2ALMNAMEN1 | |
| SCHEMBL8523457 | 0.83 | PTGS1 (0.55) | PTGS1PTGS2MAPTKMT2ALMNA | |
| SCHEMBL4486188 | 0.81 | AKR1C3 (0.50) | PTGS1PTGS2MAPTKMT2ALMNA | |
| SCHEMBL8576518 | 0.81 | PTGS1 (0.55) | PTGS1PTGS2MAPTLMNABCL2 | |
| SCHEMBL3150960 | 0.80 | PTGS2 (0.50) | PTGS1PTGS2LIG1MAPTKMT2A | |
| SCHEMBL2998970 | 0.79 | PTGS1 (0.47) | PTGS1PTGS2MAPTLMNABCL2 | |
| SCHEMBL13668901 | 0.79 | PTGS1 (0.53) | PTGS1PTGS2MAPTLMNABCL2 | |
| SCHEMBL1122739 | 0.77 | BCL2 (0.64) | PTGS1PTGS2MAPTKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0923527-A1 | A PROCESS FOR THE PREPARATION OF 2-(3-BENZOYL-PHENYL)-PROPIONIC ACID STARTING FROM ARYL-OLEFINS | Dompé S.P.A. (IT) | 1999-06-23 | — | — | EP | disclosed |
| WO-1998005623-A1 | A PROCESS FOR THE PREPARATION OF 2-ARYL-PROPIONIC AND 2-ARYL-ACETIC ACIDS STARTING FROM ARYL-OLEFINS | DOMPE' S.P.A. (IT) | 1998-02-12 | — | — | WO | disclosed |