Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.46 |
| ▸ | KCNA5 | P22460 | 7/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TACR3 | P29371 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.40 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.40 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8695732 | 0.82 | KCNA5 (0.44) | MAPTKCNA5LMNAHPGDALDH1A1 | |
| SCHEMBL2347309 | 0.82 | HPGD (0.57) | MAPTKCNA5LMNAHPGDALDH1A1 | |
| SCHEMBL3358300 | 0.81 | HPGD (0.50) | MAPTKCNA5HTTLMNAHPGD | |
| SCHEMBL6385668 | 0.77 | PTPN1 (0.42) | MAPTHTTL3MBTL1LMNAMAPK1 | |
| SCHEMBL3358387 | 0.77 | CTSA (0.49) | MAPTKCNA5MAPK1HPGDALDH1A1 | |
| SCHEMBL2789512 | 0.74 | KMT2A (0.54) | MAPTHTTL3MBTL1LMNAMAPK1 | |
| SCHEMBL15098509 | 0.74 | SMN1; SMN2 (0.54) | KCNA5L3MBTL1HPGDALDH1A1KMT2A | |
| SCHEMBL1561404 | 0.74 | SMN1; SMN2 (0.54) | KCNA5L3MBTL1HPGDALDH1A1KMT2A | |
| SCHEMBL1561401 | 0.74 | SMN1; SMN2 (0.54) | KCNA5L3MBTL1HPGDALDH1A1KMT2A | |
| SCHEMBL9223082 | 0.74 | ALDH1A1 (0.52) | MAPTHTTL3MBTL1LMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7687482-B2 | Bisphosphonate compounds and methods | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2010-03-30 | — | — | US | disclosed |