Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | GAA | P10253 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | TNF | P01375 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.44 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9228309 | 0.90 | L3MBTL1 (0.47) | KMT2AGAAALDH1A1MAPTL3MBTL1 | |
| SCHEMBL30232579 | 0.89 | KMT2A (0.54) | KMT2AGAAALDH1A1MAPTL3MBTL1 | |
| SCHEMBL617039 | 0.89 | KMT2A (0.54) | KMT2AGAAALDH1A1MAPTL3MBTL1 | |
| SCHEMBL9224006 | 0.86 | KMT2A (0.52) | KMT2AGAAALDH1A1MAPTL3MBTL1 | |
| SCHEMBL4832151 | 0.86 | GAA (0.48) | KMT2AGAAALDH1A1MAPTNPSR1 | |
| SCHEMBL9228927 | 0.85 | LMNA (0.55) | KMT2AALDH1A1MAPTL3MBTL1MEN1 | |
| SCHEMBL13196103 | 0.85 | L3MBTL1 (0.47) | KMT2AGAAALDH1A1MAPTL3MBTL1 | |
| SCHEMBL1582638 | 0.85 | HPGD (0.62) | KMT2AGAAALDH1A1MAPTMEN1 | |
| SCHEMBL19212486 | 0.84 | GAA (0.44) | KMT2AGAAALDH1A1MAPTL3MBTL1 | |
| SCHEMBL580391 | 0.84 | NPSR1 (0.48) | KMT2AGAAALDH1A1MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1419135-A4 | PROCESS FOR THE PREPARATION OF TOLTERODINE | RANBAXY LAB LTD (IN) | 2006-01-11 | — | — | EP | claimed |
| US-20040249211-A1 | PROCESS FOR THE PREPARATION OF TOLTERODINE | RANBAXY LABORATORIES LIMITED (IN) | 2004-12-09 | — | — | US | claimed |
| US-6822119-B1 | REACTING 3,4-DIHYDRO-6-METHYL-4-PHENYL-2H-BENZOPYRAN-2-ONE WITH DIMETHYL SULFATE USING PHASE TRANSFER CATALYST; DESTERIFICATION, REDUCTION, AMINATION, SULFONATION, DEPROTECTING, DECYCLIZATION, AND SALT FORMATION | RANBAXY LABORATORIES LIMITED (IN) | 2004-11-23 | — | — | US | claimed |
| EP-1419135-A1 | PROCESS FOR THE PREPARATION OF TOLTERODINE | RANBAXY LABORATORIES, LTD. (IN) | 2004-05-19 | — | — | EP | claimed |
| WO-2003014060-A1 | PROCESS FOR THE PREPARATION OF TOLTERODINE | RANBAXY LABORATORIES LIMITED (IN) | 2003-02-20 | — | — | WO | claimed |
| US-9085509-B2 | Process for preparing fesoterodine | ALEMBIC PHARMACEUTICALS LIMITED (IN) | 2015-07-21 | — | — | US | disclosed |
| US-9085509-B2 | Process for preparing fesoterodine | ALEMBIC PHARMACEUTICALS LIMITED (IN) | 2015-07-21 | — | — | US | disclosed |
| US-20140039216-A1 | PROCESS FOR PREPARING FESOTERODINE | ALEMBIC PHARMACEUTICALS LIMITED (IN) | 2014-02-06 | — | — | US | disclosed |
| US-20140039216-A1 | PROCESS FOR PREPARING FESOTERODINE | ALEMBIC PHARMACEUTICALS LIMITED (IN) | 2014-02-06 | — | — | US | disclosed |
| EP-1701932-B1 | TOLTERODINE, COMPOSITIONS AND USES THEREOF, AND PREPARATION OF THE SAME | CIPLA LTD (IN) | 2012-07-18 | — | — | EP | disclosed |
| EP-1701932-B1 | TOLTERODINE, COMPOSITIONS AND USES THEREOF, AND PREPARATION OF THE SAME | CIPLA LTD (IN) | 2012-07-18 | — | — | EP | disclosed |
| US-20120041235-A1 | PROCESS FOR THE PREPARATION OF (R)-2-(3-DIISOPROPYLAMINO)-1-PHENYLPROPYL)-4METHYLPHENOL AND SALTS THEREOF | PHARMATHEN S.A. (GR) | 2012-02-16 | — | — | US | disclosed |
| WO-2007039918-A1 | NOVEL PROCESS FOR THE PREPARATION OF TOLTERODINE | NATCO PHARMA LIMITED (IN) | 2007-04-12 | — | — | WO | disclosed |
| US-20060094904-A1 | Reacting methyl 3-(2-benzyloxy-5-methyl phenyl)-3-phenylpropionate with a reducing agent to form 3-(2-benzyloxy-5-methylphenyl)-3-phenylpropanol | DR. REDDY'S LABORATORIES LIMITED (IN) | 2006-05-04 | — | — | US | disclosed |
| US-20060079716-A1 | Process for the preparation of N,N-diisopropyl-3-(2-hydroxy-5-methylphenyl)-3-phenyl-propaneamine | CHEMI SPA (IT) | 2006-04-13 | — | — | US | disclosed |
| EP-1419135-A4 | PROCESS FOR THE PREPARATION OF TOLTERODINE | RANBAXY LAB LTD (IN) | 2006-01-11 | — | — | EP | disclosed |
| US-20040249211-A1 | PROCESS FOR THE PREPARATION OF TOLTERODINE | RANBAXY LABORATORIES LIMITED (IN) | 2004-12-09 | — | — | US | disclosed |
| US-6822119-B1 | REACTING 3,4-DIHYDRO-6-METHYL-4-PHENYL-2H-BENZOPYRAN-2-ONE WITH DIMETHYL SULFATE USING PHASE TRANSFER CATALYST; DESTERIFICATION, REDUCTION, AMINATION, SULFONATION, DEPROTECTING, DECYCLIZATION, AND SALT FORMATION | RANBAXY LABORATORIES LIMITED (IN) | 2004-11-23 | — | — | US | disclosed |
| EP-1419135-A1 | PROCESS FOR THE PREPARATION OF TOLTERODINE | RANBAXY LABORATORIES, LTD. (IN) | 2004-05-19 | — | — | EP | disclosed |
| WO-2003014060-A1 | PROCESS FOR THE PREPARATION OF TOLTERODINE | RANBAXY LABORATORIES LIMITED (IN) | 2003-02-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140039216-A1 | PROCESS FOR PREPARING FESOTERODINE | FES, QDPR, CYP4F3 | KMT2A 4345/4885GAA 1412/4885ALDH1A1 1576/4885 |
| US-20060094904-A1 | Reacting methyl 3-(2-benzyloxy-5-methyl phenyl)-3-phenylpropionate with a reducing agent to form 3-(2-benzyloxy-5-methylphenyl)-3-phenylpropanol | ADRB3, UGT1A3, COMT | KMT2A 2338/4885GAA 1532/4885ALDH1A1 1360/4885 |
| US-20040249211-A1 | PROCESS FOR THE PREPARATION OF TOLTERODINE | ADRB3, ADRA1B, ADRA2B | KMT2A 4280/4885GAA 287/4885ALDH1A1 1876/4885 |
| US-20120041235-A1 | PROCESS FOR THE PREPARATION OF (R)-2-(3-DIISOPROPYLAMINO)-1-PHENYLPROPYL)-4METHYLPHENOL AND SALTS THEREOF | PAH, UGT1A7, MLN | KMT2A 4050/4885GAA 1407/4885ALDH1A1 663/4885 |
| US-20060079716-A1 | Process for the preparation of N,N-diisopropyl-3-(2-hydroxy-5-methylphenyl)-3-phenyl-propaneamine | PNMT, INMT, DRD4 | KMT2A 1033/4885GAA 4519/4885ALDH1A1 2072/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.