Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | CDK1 | P06493 | 1/20 | 0.30 |
| ▸ | CDK2 | P24941 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL259260 | 0.73 | ALDH1A1 (0.49) | MAPK1CYP1A2ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL3646931 | 0.68 | GAA (0.39) | MAPK1LMNACYP1A2ALDH1A1KDM4E | |
| SCHEMBL23510052 | 0.66 | GAA (0.35) | MAPK1LMNACYP1A2ALDH1A1KDM4E | |
| SCHEMBL17039029 | 0.65 | ALDH1A1 (0.39) | MAPK1LMNACYP1A2ALDH1A1KDM4E | |
| SCHEMBL25276442 | 0.63 | GAA (0.39) | MAPK1ALDH1A1KDM4EGAACYP2C19 | |
| Trapidil SCHEMBL33563 | 0.61 | MAPK1 (1.00) | MAPK1LMNACYP1A2ALDH1A1KDM4E | |
| Trapidil SCHEMBL19438921 | 0.61 | MAPK1 (1.00) | MAPK1LMNACYP1A2ALDH1A1KDM4E | |
| SCHEMBL24129398 | 0.61 | LMNA (0.55) | MAPK1LMNACYP1A2ALDH1A1TP53 | |
| SCHEMBL7712316 | 0.60 | LMNA (0.54) | MAPK1LMNACYP1A2ALDH1A1TP53 | |
| Trapidil SCHEMBL6447214 | 0.60 | MAPK1 (0.97) | MAPK1LMNACYP1A2ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 8004 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260041336-A1 | PLATELET REACTIVITY EXPRESSION SCORE PREDICTS CARDIOVASCULAR RISK | NEW YORK UNIVERSITY (US) | 2026-02-12 | — | — | US | claimed |
| EP-4674894-A2 | COPOLYMERS OF N-VINYLPYRROLIDONE WITH FUNCTIONALIZED MALEIC ACID MOIETIES | Hemoteq AG (DE) | 2026-01-07 | — | — | EP | claimed |
| US-20250387396-A1 | TREATING EXTRAPYRAMIDAL SYNDROME USING TRAPIDIL | SINOPIA BIOSCIENCES INC (US) | 2025-12-25 | — | — | US | claimed |
| EP-4663688-A2 | CROSSLINKERS | Hemoteq AG (DE) | 2025-12-17 | — | — | EP | claimed |
| EP-4630413-A1 | FLAVANONE COMPOUNDS AND THEIR USE AS FLAVOR MODIFIERS | Firmenich Incorporated (US) | 2025-10-15 | — | — | EP | claimed |
| US-20250271426-A1 | REDUCTION OF BITTER TASTE OF ACTIVE PHARMACEUTICAL INGREDIENTS AND RELATED ASSAYS AND SCREENING METHODS | FIRMENICH INCORPORATED (US) | 2025-08-28 | — | — | US | claimed |
| EP-3442538-B1 | TREATING LEVODOPA-INDUCED DYSKINESIA USING TRAPIDIL | SINOPIA BIOSCIENCES INC (US) | 2025-07-23 | — | — | EP | claimed |
| WO-2025111482-A1 | COMPLEXING AGENT SALT FORMULATIONS OF PHARMACEUTICAL COMPOUNDS AT LOW STOICHIOMETRIC RATIOS | BEXSON BIOMEDICAL, INC. (US) | 2025-05-30 | — | — | WO | claimed |
| US-12285488-B2 | Oral dosage form containing theobromine-free cocoa | LTS LOHMANN THERAPIE-SYSTEME AG (DE) | 2025-04-29 | — | — | US | claimed |
| US-12268691-B2 | Treating extrapyramidal syndrome using trapidil | SINOPIA BIOSCIENCES, INC. (US) | 2025-04-08 | — | — | US | claimed |
| EP-0301423-B1 | Pharmaceutical compositions containing trapidil, and process for their preparation | CHIESI FARMA SPA (IT) | 1994-04-27 | — | — | EP | claimed |
| WO-1994006416-A1 | PHARMACEUTICAL TABLET CAPABLE OF LIBERATING ONE OR MORE DRUGS AT DIFFERENT RELEASE RATES | JAGOTEC AG (CH) | 1994-03-31 | — | — | WO | claimed |
| US-5288503-A | WATER-PERMEABLE DIFFUSION BARRIER OF POLYVINYL ALCOHOL | SRCHEM INCORPORATED (US) | 1994-02-22 | — | — | US | claimed |
| WO-1993023082-A1 | TOPICAL OPHTHALMIC COMPOSITIONS COMPRISING A COMBINATION OF CALCIUM ANTAGONISTS WITH KNOWN ANTIGLAUCOMA AGENTS | ALCON LABORATORIES, INC. (US) | 1993-11-25 | — | — | WO | claimed |
| US-5260066-A | Cryogel bandage containing therapeutic agent | SRCHEM INCORPORATED (US) | 1993-11-09 | — | — | US | claimed |
| EP-0568451-A1 | Thermoplastic polymer composition and medical devices made of the same | TERUMO KABUSHIKI KAISHA (JP) | 1993-11-03 | — | — | EP | claimed |
| EP-0518940-A4 | METHOD AND APPARATUS FOR TREATMENT OF TUBULAR ORGANS | — | 1993-05-12 | — | — | EP | claimed |
| EP-0518940-A1 | METHOD AND APPARATUS FOR TREATMENT OF TUBULAR ORGANS | ENDOLUMINAL THERAPEUTICS, INC. (US) | 1992-12-23 | — | — | EP | claimed |
| WO-1991012846-A1 | METHOD AND APPARATUS FOR TREATMENT OF TUBULAR ORGANS | SLEPIAN MARVIN J (US) | 1991-09-05 | — | — | WO | claimed |
| EP-0301423-A1 | Pharmaceutical compositions containing trapidil, and process for their preparation | CHIESI FARMACEUTICI S.p.A. (IT) | 1989-02-01 | — | — | EP | claimed |