Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | RECQL | P46063 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | GMNN | O75496 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1284435 | 0.73 | KMT2A (0.32) | KDM4ELMNAMAPTTSHRBACE1 | |
| SCHEMBL11374577 | 0.69 | ALOX15 (0.31) | TSHRALOX15 | |
| SCHEMBL30839467 | 0.69 | KDM4E (0.32) | KDM4ELMNAMAPTHCRTR1 | |
| SCHEMBL10446780 | 0.69 | KDM4E (0.36) | KDM4ELMNAMAPTHCRTR1ALDH1A1 | |
| SCHEMBL30599789 | 0.69 | KDM4E (0.32) | KDM4ELMNAMAPTHCRTR1 | |
| SCHEMBL17784279 | 0.67 | NPSR1 (0.37) | KDM4ELMNAMAPTHCRTR1ALDH1A1 | |
| SCHEMBL7846849 | 0.67 | KDM4E (0.31) | KDM4ELMNAMAPTHCRTR1 | |
| SCHEMBL11512857 | 0.67 | HTR2B (0.32) | KDM4ELMNAMAPTHCRTR1 | |
| SCHEMBL9729700 | 0.66 | LMNA (0.32) | LMNA | |
| SCHEMBL25267081 | 0.65 | KDM4E (0.31) | KDM4ELMNAMAPTHCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100133098-A1 | Methods and Devices for Concentration and Purification of Analytes for Chemical Analysis Including Matrix-Assisted Laser Desportion/Ionization (MALDI) Mass Spectrometry (MS) | PROTEIN DISCOVERY, INC. | 2010-06-03 | — | — | US | disclosed |
| US-7534338-B2 | Methods and devices for concentration and purification of analytes for chemical analysis including matrix-assisted laser desorption/ionization(MALDI) mass spectrometry (MS) | PROTEIN DISCOVERY, INC. (US) | 2009-05-19 | — | — | US | disclosed |
| EP-1676292-A4 | METHODS AND DEVICES FOR CONCENTRATION AND PURIFICATION OF ANALYTES FOR CHEMICAL ANALYSIS INCLUDING MATRIX-ASSISTED LASER DESORPTION/IONIZATION (MALDI) MASS SPECTROMETRY (MS) | PROTEIN DISCOVERY INC (US) | 2009-01-07 | — | — | EP | disclosed |
| CN-1890774-A | Method and apparatus for enrichment and purification of analytes for chemical analysis including matrix-assisted laser desorption/ionization (MALDI) mass spectrometry (MS) analysis | PROTEIN DISCOVERY INC (US) | 2007-01-03 | — | — | CN | disclosed |
| EP-1676292-A2 | METHODS AND DEVICES FOR CONCENTRATION AND PURIFICATION OF ANALYTES FOR CHEMICAL ANALYSIS INCLUDING MATRIX-ASSISTED LASER DESORPTION/IONIZATION (MALDI) MASS SPECTROMETRY (MS) | Protein Discovery Inc. (US) | 2006-07-05 | — | — | EP | disclosed |
| US-20050116161-A1 | Methods and devices for concentration and purification of analytes for chemical analysis including matrix-assisted laser desorption/ionization (MALDI) mass spectrometry (MS) | PROTEIN DISCOVERY, INC. (US) | 2005-06-02 | — | — | US | disclosed |
| WO-2005036132-A2 | METHODS AND DEVICES FOR CONCENTRATION AND PURIFICATION OF ANALYTES FOR CHEMICAL ANALYSIS INCLUDING MATRIX-ASSISTED LASER DESORPTION/IONIZATION (MALDI) MASS SPECTROMETRY (MS) | PROTEIN DISCOVERY, INC. (US) | 2005-04-21 | — | — | WO | disclosed |